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10.1016/j.smim.2016.10.004

http://scihub22266oqcxt.onion/10.1016/j.smim.2016.10.004
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C5333784!5333784!27771140
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suck abstract from ncbi


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pmid27771140      Semin+Immunol 2016 ; 28 (5): 417-24
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  • Integrating Immunometabolism and Macrophage Diversity #MMPMID27771140
  • Artyomov M; Sergushichev A; Schilling JD
  • Semin Immunol 2016[Oct]; 28 (5): 417-24 PMID27771140show ga
  • Macrophages are heterogeneous cells that play a key role in inflammatory and tissue reparative responses. Over the past decade it has become clear that shifts in cellular metabolism are important determinants of macrophage function and phenotype. At the same time, our appreciation of macrophage diversity in vivo has also been increasing. Factors such as cell origin and tissue localization are now recognized as important variables that influence macrophage biology. Whether different macrophage populations also have unique metabolic phenotypes has not been extensively explored. In this article, we will discuss the importance of understanding how macrophage origin can modulate metabolic programming and influence inflammatory responses.
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