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10.3390/genes8020053 http://scihub22266oqcxt.onion/10.3390/genes8020053 C5333042!5333042!28134823     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Genes+(Basel) 2017 ; 8 (2): ä Nephropedia Template TP {{tp|p=28134823|t=2017. Correction of Monogenic and Common Retinal Disorders with Gene Therapy |pdf=|usr=}}{{28134823}} gab.com Text Correction of Monogenic and Common Retinal Disorders with Gene Therapy JO: Genes (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=28134823 #FOAvip The past decade has seen major advances in gene-based therapies, many of which show promise for translation to human disease. At the forefront of research in this field is ocular disease, as the eye lends itself to gene-based interventions due to its accessibility, relatively immune-privileged status, and ability to be non-invasively monitored. A landmark study in 2001 demonstrating successful gene therapy in a large-animal model for Leber congenital amaurosis set the stage for translation of these strategies from the bench to the bedside. Multiple clinical trials have since initiated for various retinal diseases, and further improvements in gene therapy techniques have engendered optimism for alleviating inherited blinding disorders. This article provides an overview of gene-based strategies for retinal disease, current clinical trials that engage these strategies, and the latest techniques in genome engineering, which could serve as the next frontline of therapeutic interventions. Twit Text FOAVip Correction of Monogenic and Common Retinal Disorders with Gene Therapy ????Genes (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=28134823 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28134823 #FOAvip English Wikipedia <ref>{{Cite pmid|28134823}}</ref> Correction of Monogenic and Common Retinal Disorders with Gene Therapy #MMPMID28134823 Sengillo JD; Justus S; Cabral T; Tsang SH Genes (Basel) 2017[Feb]; 8 (2): ä PMID28134823show ga The past decade has seen major advances in gene-based therapies, many of which show promise for translation to human disease. At the forefront of research in this field is ocular disease, as the eye lends itself to gene-based interventions due to its accessibility, relatively immune-privileged status, and ability to be non-invasively monitored. A landmark study in 2001 demonstrating successful gene therapy in a large-animal model for Leber congenital amaurosis set the stage for translation of these strategies from the bench to the bedside. Multiple clinical trials have since initiated for various retinal diseases, and further improvements in gene therapy techniques have engendered optimism for alleviating inherited blinding disorders. This article provides an overview of gene-based strategies for retinal disease, current clinical trials that engage these strategies, and the latest techniques in genome engineering, which could serve as the next frontline of therapeutic interventions. äCorrection of Monogenic and Common Retinal Disorders with Gene Therapy(epmc).pdf DeepDyve Pubget Overpricing