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10.1517/14728222.2015.1073261 http://scihub22266oqcxt.onion/10.1517/14728222.2015.1073261 C5332544!5332544!26245678     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Expert+Opin+Ther+Targets 2015 ; 19 (12): 1637-50 Nephropedia Template TP {{tp|p=26245678|t=2015. Effect of bacterial and host factors on Helicobacter pylori eradication therapy |pdf=|usr=}}{{26245678}} gab.com Text Effect of bacterial and host factors on Helicobacter pylori eradication therapy JO: Expert Opin Ther Targets http://www.kidney.de/pget.php?&tw=1&pmid=26245678 #FOAvip Introduction: A clearer understanding of the factors affecting the cure rate of Helicobacter pylori infection might lead to the development of novel prevention strategies and therapeutic targets. Areas covered: This review covers two important issues that affect the eradication of H. pylori: bacterial and host factors. Several virulence factors have been shown to be predictors for gastroduodenal diseases. Successful treatment of H. pylori infection also depends on host genetic factors such as cytochrome P450 2C19 (CYP2C19) and interleukin (IL)-1B. The latest evidence on host genetic factors is discussed. Expert opinion: The authors identify three main targets for achieving effective eradication therapy. The first therapeutic target is to identify counter measures for antibiotic-resistant H. pylori strains. Thus, antibiotic susceptibility should be checked in all patients, ideally, before the start of eradication treatment. The second therapeutic target is the inhibition of acid suppression. Maintaining a high intragastric pH for 24 hours increases the effectiveness of some antibiotics and the eradication effects for H. pylori. The third therapeutic target is to identify high-risk groups; the CYP2C19 and IL-1B polymorphisms are candidates for significant risk factors. A personalized medical approach will likely increase the cure rate of H. pylori infection. Twit Text FOAVip Effect of bacterial and host factors on Helicobacter pylori eradication therapy ????Expert Opin Ther Targets http://www.kidney.de/pget.php?&tw=1&pmid=26245678 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26245678 #FOAvip English Wikipedia <ref>{{Cite pmid|26245678}}</ref> Effect of bacterial and host factors on Helicobacter pylori eradication therapy #MMPMID26245678 Uotani T; Miftahussurur M; Yamaoka Y Expert Opin Ther Targets 2015[]; 19 (12): 1637-50 PMID26245678show ga Introduction: A clearer understanding of the factors affecting the cure rate of Helicobacter pylori infection might lead to the development of novel prevention strategies and therapeutic targets. Areas covered: This review covers two important issues that affect the eradication of H. pylori: bacterial and host factors. Several virulence factors have been shown to be predictors for gastroduodenal diseases. Successful treatment of H. pylori infection also depends on host genetic factors such as cytochrome P450 2C19 (CYP2C19) and interleukin (IL)-1B. The latest evidence on host genetic factors is discussed. Expert opinion: The authors identify three main targets for achieving effective eradication therapy. The first therapeutic target is to identify counter measures for antibiotic-resistant H. pylori strains. Thus, antibiotic susceptibility should be checked in all patients, ideally, before the start of eradication treatment. The second therapeutic target is the inhibition of acid suppression. Maintaining a high intragastric pH for 24 hours increases the effectiveness of some antibiotics and the eradication effects for H. pylori. The third therapeutic target is to identify high-risk groups; the CYP2C19 and IL-1B polymorphisms are candidates for significant risk factors. A personalized medical approach will likely increase the cure rate of H. pylori infection. äEffect of bacterial and host factors on Helicobacter pylori eradicatio(epmc).pdf DeepDyve Pubget Overpricing