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2017 ; 7
(ä): 29
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Treating the Critically Ill with Radiotherapy: Lessons Learned from a Young Woman
with Cardiac Angiosarcoma
#MMPMID28303236
Fields EC
; Squires B
; Lomas H
Front Oncol
2017[]; 7
(ä): 29
PMID28303236
show ga
BACKGROUND: Treating patients who are critically ill with radiotherapy (RT)
brings a unique set of challenges as it involves treating patients who require
mechanical life support, unconventional positioning, and a multidisciplinary team
approach to ensure safety. However, when the benefits of such treatment outweigh
the risks, the challenges can be overcome, as demonstrated in this unique case of
cardiac angiosarcoma. CASE DESCRIPTION: This is a case of a 42-year-old female
with a right sided cardiac angiosarcoma who quickly developed cardiac tamponade
and respiratory failure related to compression of her right heart by the tumor.
She was treated with high dose single fraction RT initially and had a clinical
response allowing further conformal RT with concurrent chemotherapy. DISCUSSION:
Managing critically ill patients requires creativity, improvisation, and careful
consideration of existing evidence. Although limited, the data suggest that
multi-modality therapy with a combination of surgery, RT, and chemotherapy
provide the best outcomes.