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10.1172/JCI84417 http://scihub22266oqcxt.onion/10.1172/JCI84417 C5330729!5330729 !28248203     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28248203 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28248203 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       J+Clin+Invest 2017 ; 127 (3 ): 737-749 Nephropedia Template TP {{tp|p=28248203 |t=2017. Chikungunya virus: epidemiology, replication, disease mechanisms, and prospective intervention strategies |pdf=|usr=}}{{28248203 }} gab.com Text Chikungunya virus: epidemiology, replication, disease mechanisms, and prospective intervention strategies JO: J Clin Invest http://www.kidney.de/pget.php?&tw=1&pmid=28248203 #FOAvip Chikungunya virus (CHIKV), a reemerging arbovirus, causes a crippling musculoskeletal inflammatory disease in humans characterized by fever, polyarthralgia, myalgia, rash, and headache. CHIKV is transmitted by Aedes species of mosquitoes and is capable of an epidemic, urban transmission cycle with high rates of infection. Since 2004, CHIKV has spread to new areas, causing disease on a global scale, and the potential for CHIKV epidemics remains high. Although CHIKV has caused millions of cases of disease and significant economic burden in affected areas, no licensed vaccines or antiviral therapies are available. In this Review, we describe CHIKV epidemiology, replication cycle, pathogenesis and host immune responses, and prospects for effective vaccines and highlight important questions for future research. Twit Text FOAVip Chikungunya virus: epidemiology, replication, disease mechanisms, and prospective intervention strategies ????J Clin Invest http://www.kidney.de/pget.php?&tw=1&pmid=28248203 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28248203 #FOAvip English Wikipedia <ref>{{Cite pmid|28248203 }}</ref> Chikungunya virus: epidemiology, replication, disease mechanisms, and prospective intervention strategies #MMPMID28248203 Silva LA ; Dermody TS J Clin Invest 2017[Mar]; 127 (3 ): 737-749 PMID28248203 show ga Chikungunya virus (CHIKV), a reemerging arbovirus, causes a crippling musculoskeletal inflammatory disease in humans characterized by fever, polyarthralgia, myalgia, rash, and headache. CHIKV is transmitted by Aedes species of mosquitoes and is capable of an epidemic, urban transmission cycle with high rates of infection. Since 2004, CHIKV has spread to new areas, causing disease on a global scale, and the potential for CHIKV epidemics remains high. Although CHIKV has caused millions of cases of disease and significant economic burden in affected areas, no licensed vaccines or antiviral therapies are available. In this Review, we describe CHIKV epidemiology, replication cycle, pathogenesis and host immune responses, and prospects for effective vaccines and highlight important questions for future research. |*Chikungunya Fever/epidemiology/immunology/metabolism/transmission [MESH] |Aedes/virology [MESH] |Animals [MESH] |Chikungunya virus/*pathogenicity/*physiology [MESH] |Humans [MESH]Chikungunya virus: epidemiology, replication, disease mechanisms, and (epmc).pdf DeepDyve Pubget Overpricing