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10.1364/BOE.8.001036

http://scihub22266oqcxt.onion/10.1364/BOE.8.001036
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C5330557!5330557!28271001
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suck abstract from ncbi


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pmid28271001      Biomed+Opt+Express 2017 ; 8 (2): 1036-44
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  • Fully integrated optical coherence tomography, ultrasound, and indocyanine green-based fluorescence tri-modality system for intravascular imaging #MMPMID28271001
  • Li Y; Jing J; Qu Y; Miao Y; Zhang B; Ma T; Yu M; Zhou Q; Chen Z
  • Biomed Opt Express 2017[Feb]; 8 (2): 1036-44 PMID28271001show ga
  • We present a tri-modality imaging system and fully integrated tri-modality probe for intravascular imaging. The tri-modality imaging system is able to simultaneously acquire optical coherence tomography (OCT), ultrasound (US), and fluorescence imaging. Moreover, for fluorescence imaging, we used the FDA-approved indocyanine green (ICG) dye as the contrast agent to target lipid-loaded macrophages. We conducted imaging from a male New Zealand white rabbit to evaluate the performance of the tri-modality system. In addition, tri-modality images of rabbit aortas were correlated with hematoxylin and eosin (H&E) histology to check the measurement accuracy. The fully integrated miniature tri-modality probe, together with the use of ICG dye suggest that the system is of great potential for providing a more accurate assessment of vulnerable plaques in clinical applications.
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