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10.1186/s13045-017-0430-2 http://scihub22266oqcxt.onion/10.1186/s13045-017-0430-2 C5329931!5329931!28241846     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Hematol+Oncol 2017 ; 10 (ä): ä Nephropedia Template TP {{tp|p=28241846|t=2017. Tumor-associated macrophages: from basic research to clinical application |pdf=|usr=}}{{28241846}} gab.com Text Tumor-associated macrophages: from basic research to clinical application JO: J Hematol Oncol http://www.kidney.de/pget.php?&tw=1&pmid=28241846 #FOAvip The fact that various immune cells, including macrophages, can be found in tumor tissues has long been known. With the introduction of concept that macrophages differentiate into a classically or alternatively activated phenotype, the role of tumor-associated macrophages (TAMs) is now beginning to be elucidated. TAMs act as ?protumoral macrophages,? contributing to disease progression. TAMs can promote initiation and metastasis of tumor cells, inhibit antitumor immune responses mediated by T cells, and stimulate tumor angiogenesis and subsequently tumor progression. As the relationship between TAMs and malignant tumors becomes clearer, TAMs are beginning to be seen as potential biomarkers for diagnosis and prognosis of cancers, as well as therapeutic targets in these cases. In this review, we will discuss the origin, polarization, and role of TAMs in human malignant tumors, as well as how TAMs can be used as diagnostic and prognostic biomarkers and therapeutic targets of cancer in clinics. Twit Text FOAVip Tumor-associated macrophages: from basic research to clinical application ????J Hematol Oncol http://www.kidney.de/pget.php?&tw=1&pmid=28241846 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28241846 #FOAvip English Wikipedia <ref>{{Cite pmid|28241846}}</ref> Tumor-associated macrophages: from basic research to clinical application #MMPMID28241846 Yang L; Zhang Y J Hematol Oncol 2017[]; 10 (ä): ä PMID28241846show ga The fact that various immune cells, including macrophages, can be found in tumor tissues has long been known. With the introduction of concept that macrophages differentiate into a classically or alternatively activated phenotype, the role of tumor-associated macrophages (TAMs) is now beginning to be elucidated. TAMs act as ?protumoral macrophages,? contributing to disease progression. TAMs can promote initiation and metastasis of tumor cells, inhibit antitumor immune responses mediated by T cells, and stimulate tumor angiogenesis and subsequently tumor progression. As the relationship between TAMs and malignant tumors becomes clearer, TAMs are beginning to be seen as potential biomarkers for diagnosis and prognosis of cancers, as well as therapeutic targets in these cases. In this review, we will discuss the origin, polarization, and role of TAMs in human malignant tumors, as well as how TAMs can be used as diagnostic and prognostic biomarkers and therapeutic targets of cancer in clinics. äTumor-associated macrophages: from basic research to clinical applicat(epmc).pdf DeepDyve Pubget Overpricing