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10.1155/2017/5096741 http://scihub22266oqcxt.onion/10.1155/2017/5096741 C5329689!5329689!28286780     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Immunol+Res 2017 ; 2017 (ä): ä Nephropedia Template TP {{tp|p=28286780|t=2017. IL-1? and IL-6 Are Highly Expressed in RF+IgE+ Systemic Lupus Erythematous Subtype |pdf=|usr=}}{{28286780}} gab.com Text IL-1 and IL-6 Are Highly Expressed in RF+IgE+ Systemic Lupus Erythematous Subtype JO: J Immunol Res http://www.kidney.de/pget.php?&tw=1&pmid=28286780 #FOAvip Background. Systemic lupus erythematosus (SLE) is an autoimmune disease with great heterogeneity in pathogenesis and clinical symptoms. Rheumatoid factor (RF) is one key indicator for rheumatoid arthritis (RA) while immunoglobulin E (IgE) is associated with type I hypersensitivity. To better categorize SLE subtypes, we determined the dominant cytokines based on familial SLE patients. Methods. RF, IgE, and multiple cytokines (i.e., IL-1?, IL-6, IL-8, IL-10, IL-17, IFN-?, IP-10, MCP-1, and MIP-1?) were measured in sera of familial SLE patients (n = 3), noninherited SLE patients (n = 108), and healthy controls (n = 80). Results. Three familial SLE patients and 5 noninherited SLE cases are with features of RF+IgE+. These RF+IgE+ SLE patients expressed significantly higher levels of IL-1? and IL-6 than the other SLE patients (P < 0.05). IL-6 correlated with both IgE and IL-1? levels in RF+IgE+ SLE patients (r2 = 0.583, P = 0.027; r2 = 0.847, P = 0.001), and IgE also correlated with IL-1? (r2 = 0.567, P = 0.031). Conclusion. Both IL-1? and IL-6 are highly expressed cytokines in RF+IgE+ SLE subtype which may be related to the pathogenesis of this special SLE subtype and provide accurate treatment strategy by neutralizing IL-1? and IL-6. Twit Text FOAVip IL-1 and IL-6 Are Highly Expressed in RF+IgE+ Systemic Lupus Erythematous Subtype ????J Immunol Res http://www.kidney.de/pget.php?&tw=1&pmid=28286780 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28286780 #FOAvip English Wikipedia <ref>{{Cite pmid|28286780}}</ref> IL-1? and IL-6 Are Highly Expressed in RF+IgE+ Systemic Lupus Erythematous Subtype #MMPMID28286780 Wu Y; Cai B; Zhang J; Shen B; Huang Z; Tan C; Baan CC; Wang L J Immunol Res 2017[]; 2017 (ä): ä PMID28286780show ga Background. Systemic lupus erythematosus (SLE) is an autoimmune disease with great heterogeneity in pathogenesis and clinical symptoms. Rheumatoid factor (RF) is one key indicator for rheumatoid arthritis (RA) while immunoglobulin E (IgE) is associated with type I hypersensitivity. To better categorize SLE subtypes, we determined the dominant cytokines based on familial SLE patients. Methods. RF, IgE, and multiple cytokines (i.e., IL-1?, IL-6, IL-8, IL-10, IL-17, IFN-?, IP-10, MCP-1, and MIP-1?) were measured in sera of familial SLE patients (n = 3), noninherited SLE patients (n = 108), and healthy controls (n = 80). Results. Three familial SLE patients and 5 noninherited SLE cases are with features of RF+IgE+. These RF+IgE+ SLE patients expressed significantly higher levels of IL-1? and IL-6 than the other SLE patients (P < 0.05). IL-6 correlated with both IgE and IL-1? levels in RF+IgE+ SLE patients (r2 = 0.583, P = 0.027; r2 = 0.847, P = 0.001), and IgE also correlated with IL-1? (r2 = 0.567, P = 0.031). Conclusion. Both IL-1? and IL-6 are highly expressed cytokines in RF+IgE+ SLE subtype which may be related to the pathogenesis of this special SLE subtype and provide accurate treatment strategy by neutralizing IL-1? and IL-6. äIL-1? and IL-6 Are Highly Expressed in RF+IgE+ Systemic Lupus Erythema(epmc).pdf DeepDyve Pubget Overpricing