Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27744012
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Bone
2017 ; 96
(ä): 85-90
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Serum sclerostin decreases following 12months of resistance- or jump-training in
men with low bone mass
#MMPMID27744012
Hinton PS
; Nigh P
; Thyfault J
Bone
2017[Mar]; 96
(ä): 85-90
PMID27744012
show ga
PURPOSE: We previously reported that 12months of resistance training (RT, 2×/wk,
N=19) or jump training (JUMP, 3×/wk, N=19) increased whole body and lumbar spine
BMD and increased serum bone formation markers relative to resorption in
physically active (?4h/wk) men (mean age: 44±2y; median: 44y) with osteopenia of
the hip or spine. The purpose of this secondary analysis was to examine the
effects of the RT or JUMP intervention on potential endocrine mediators of the
exercise effects on bone, specifically IGF-I, PTH and sclerostin. METHODS:
Fasting blood samples were collected after a 24-h period of no exercise at
baseline and after 12months of RT or JUMP. IGF-I, PTH and sclerostin were
measured in serum by ELISA. The effects of RT or JUMP on IGF-I, PTH and
sclerostin were evaluated using 2×2 repeated measures ANOVA (time, group). This
study was conducted in accordance with the Declaration of Helsinki and was
approved by the University of Missouri IRB. RESULTS: Sclerostin concentrations in
serum significantly decreased and IGF-I significantly increased after 12months of
RT or JUMP; while PTH remained unchanged. CONCLUSION: The beneficial effects of
long-term, progressive-intensity RT or JUMP on BMD in moderately active men with
low bone mass are associated with decreased sclerostin and increased IGF-I.