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10.1038/nri.2016.147

http://scihub22266oqcxt.onion/10.1038/nri.2016.147
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C5328506!5328506!28138137
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suck abstract from ncbi

pmid28138137      Nat+Rev+Immunol 2017 ; 17 (3): 151-64
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  • Programmed cell death as a defence against infection #MMPMID28138137
  • Jorgensen I; Rayamajhi M; Miao EA
  • Nat Rev Immunol 2017[Mar]; 17 (3): 151-64 PMID28138137show ga
  • Eukaryotic cells can die from physical trauma, resulting in necrosis. Alternately, they can die via programmed cell death upon stimulation of specific signalling pathways. Here we discuss the utility of four cell death pathways in innate immune defence against bacterial and viral infection: apoptosis, necroptosis, pyroptosis and NETosis. We describe the interactions that interweave different programmed cell death pathways, which create complex signalling networks that cross-guard each other in the evolutionary arms race with pathogens. Finally, we describe how the resulting cell corpses ? apoptotic bodies, pore-induced intracellular traps (PITs) and neutrophil extracellular traps (NETs) ? promote clearance of infection.
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