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10.2147/TCRM.S129133

http://scihub22266oqcxt.onion/10.2147/TCRM.S129133
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suck abstract from ncbi


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pmid28260912
      Ther+Clin+Risk+Manag 2017 ; 13 (ä): 255-262
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  • Association of uremic pruritus in hemodialysis patients with the number of days of high mean 24-hour particulate matter with a diameter of 2 5 ?m #MMPMID28260912
  • Liu MH ; Chan MJ ; Hsu CW ; Weng CH ; Yen TH ; Huang WH
  • Ther Clin Risk Manag 2017[]; 13 (ä): 255-262 PMID28260912 show ga
  • Uremic pruritus (UP) is a common and incapacitating symptom in patients undergoing hemodialysis (HD). The pathogenesis of UP is multifactorial and complex. Particulate matter (PM), a major air pollutant, is a mixture of particles with various chemical compositions. PM is associated with several allergic diseases, including dermatitis. To assess the role of PM (PM with a diameter of <10 ?m [PM(10)] and PM with a diameter of <2.5 ?m [PM(2.5)]) and other clinical variables in UP in patients on HD, we recruited 866 patients on maintenance HD (MHD). We analyzed the number of days of mean 24-hour PM(10) ?125 ?g/m(3)/12 months (NDPM(10)) or the number of days of mean 24-hour PM(2.5) ?35 ?g/m(3)/12 months (NDPM(2.5)) exceeding the standard level in the past 12 months respectively to determine the association with UP. In a multivariate logistic regression, HD duration, serum ferritin levels, low-density lipoprotein (LDL) levels, and NDPM(2.5) ?116 days/12 months were positively associated with UP. This cross-sectional study showed that the number of days on which the environmental PM(2.5) exceeds the standard level might be associated with UP in patients on MHD.
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