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10.1097/MAT.0000000000000464

http://scihub22266oqcxt.onion/10.1097/MAT.0000000000000464
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C5327860!5327860!27831998
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suck abstract from ncbi


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pmid27831998      ASAIO+J 2017 ; 63 (2): 123-7
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  • Hemodynamic Performance of a Novel Right Ventricular Assist Device (PERKAT) #MMPMID27831998
  • Kretzschmar D; Schulze PC; Ferrari MW
  • ASAIO J 2017[Mar]; 63 (2): 123-7 PMID27831998show ga
  • Acute right ventricular failure (RVF) is an increasing clinical problem and a life-threatening condition. Right ventricular assist devices represent a reasonable treatment option for patients with refractory RVF. We here present a novel percutaneously implantable device for right ventricular support. The PERKAT device is based on a nitinol stent cage, which is covered with valve-carrying foils. A flexible outlet trunk with a pigtail tip is connected to the distal part. The device is driven by an intra-aortic balloon pump (IABP) drive unit, which inflates/deflates a standard IABP-balloon placed within the stent cage. In-vitro evaluation was done in a liquid bath containing water or blood analog. The PERKAT device was tested in different afterload settings using two different IABP-balloons and varying inflation/deflation rates. We detected flow rates ranging from 1.97 to 3.93?L/min depending on the afterload setting, inflation/deflation rate, balloon size, and the medium used. Flow rates between water and blood analog were nearly comparable, and in the higher inflation/deflation rate settings slightly higher with water. Based on this promising in vitro data, the innovative percutaneously implantable PERKAT device has a potential to become a therapeutic option for patients with RVF refractory to medical treatment.
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