Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28261358
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Maedica+(Bucur)
2015 ; 10
(3
): 226-230
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Improving Melanoma Path Reports: the Importance of Histopathological Parameters
in Diagnosis of Cutaneous Melanoma
#MMPMID28261358
Avram AM
; Simionescu OD
; Costache M
; Grigore M
Maedica (Bucur)
2015[Sep]; 10
(3
): 226-230
PMID28261358
show ga
BACKGROUND: Despite the fact that melanoma is an easy approachable tumor for
diagnosis, the incidence of this skin cancer is still increasing.
Histopathological assessment of melanocytic tumors is the gold standard in
melanoma diagnosis and represents a problematic aspect of dermatology and
pathology. Over the past decades many efforts have been made in determining
histological characteristics influencing the prognosis and survival of patients
with clinically localized primary melanoma. Some of these parameters also proved
to be essential for tumor staging and choosing adequate clinical management.
OBJECTIVE: We present a retrospective study of 21 melanoma cases with
histopathological errors or incomplete path reports, with the intention to raise
awareness about the importance of an accurate diagnosis for the management of
these cases and for patient prognosis. METHODS: We retrospectively reviewed data
from pathology reports and discharge medical records from 21 patients diagnosed
with melanoma between 2006 and 2014 and treated in other hospitals that presented
in our clinic for second opinion. All slides were reviewed by an authorized
dermatopathologist and the new path report was compared with the other ones,
presented by the patients. RESULTS: The majority of the path reports were
incomplete, with absent (35.7%) or wrong (35.7%) tumor thickness, making
impossible to stage the tumor. Absence of histopathological diagnosis was noticed
in 3 cases and a wrong diagnosis was determined in 3 patients. Other missing
parameters were ulceration status, mitotic rate, microsatellitosis and surgical
margins evaluation. missing or incorrect determined in half of the cases.
CONCLUSIONS: This study presents the fact that there is a lack of relevant
information in the path reports of melanoma cases, making impossible to stage and
treat this patients, with adverse clinical impact. We want to emphasize the
importance of a standardized histopathological evaluation of melanocytic tumors,
consistent with the generally accepted standards, leading to improved healthcare
quality and reduced medico legal risks associated with melanoma.