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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Anal+Biochem
2017 ; 529
(ä): 171-178
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In vivo(17)O MRS imaging - Quantitative assessment of regional oxygen consumption
and perfusion rates in living brain
#MMPMID27568551
Zhu XH
; Chen W
Anal Biochem
2017[Jul]; 529
(ä): 171-178
PMID27568551
show ga
In the last decade, in vivo oxygen-17 ((17)O) MRS has evolved into a promising MR
technique for noninvasively studying oxygen metabolism and perfusion in aerobic
organs with the capability of imaging the regional metabolic rate of oxygen and
its changes. In this chapter, we will briefly review the methodology of the
in vivo(17)O MRS technique and its recent development and applications; we will
also discuss the advantages of the high/ultrahigh magnetic field for (17)O MR
detection, as well as the challenges and potential of this unique MRS method for
biomedical research of oxygen metabolism, mitochondrial function and tissue
energetics in health and disease.