10.1002/hbm.23440 http://scihub22266oqcxt.onion/10.1002/hbm.23440 C5326664!5326664!27785847 free free free
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Hum+Brain+Mapp 2017 ; 38 (3): 1125-39 Nephropedia Template TP gab.com Text Twit Text FOAVip Twit Text # English Wikipedia
Default mode network deactivation during odor?visual association #MMPMID27785847Karunanayaka PR; Wilson DA; Tobia MJ; Martinez BE; Meadowcroft MD; Eslinger PJ; Yang QX Hum Brain Mapp 2017[Mar]; 38 (3): 1125-39 PMID27785847show ga
Default mode network (DMN) deactivation has been shown to be functionally relevant for goal?directed cognition. In this study, the DMN's role during olfactory processing was investigated using two complementary functional magnetic resonance imaging (fMRI) paradigms with identical timing, visual?cue stimulation, and response monitoring protocols. Twenty?nine healthy, non?smoking, right?handed adults (mean age?=?26?±?4 years, 16 females) completed an odor?visual association fMRI paradigm that had two alternating odor?+?visual and visual?only trial conditions. During odor?+?visual trials, a visual cue was presented simultaneously with an odor, while during visual?only trial conditions the same visual cue was presented alone. Eighteen of the twenty?nine participants (mean age?=?27.0?±?6.0 years, 11 females) also took part in a control no?odor fMRI paradigm that consisted of a visual?only trial condition which was identical to the visual?only trials in the odor?visual association paradigm. Independent Component Analysis (ICA), extended unified structural equation modeling (euSEM), and psychophysiological interaction (PPI) were used to investigate the interplay between the DMN and olfactory network. In the odor?visual association paradigm, DMN deactivation was evoked by both the odor?+?visual and visual?only trial conditions. In contrast, the visual?only trials in the no?odor paradigm did not evoke consistent DMN deactivation. In the odor?visual association paradigm, the euSEM and PPI analyses identified a directed connectivity between the DMN and olfactory network which was significantly different between odor?+?visual and visual?only trial conditions. The results support a strong interaction between the DMN and olfactory network and highlights the DMN's role in task?evoked brain activity and behavioral responses during olfactory processing. Hum Brain Mapp 38:1125?1139, 2017. © 2016 Wiley Periodicals, Inc.Please enable JavaScript to view the comments powered by Disqus. ä DeepDyve Pubget Overpricing