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10.1007/s00401-016-1635-0 http://scihub22266oqcxt.onion/10.1007/s00401-016-1635-0 C5325834!5325834!27771772     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Acta+Neuropathol 2017 ; 133 (3): 409-15 Nephropedia Template TP {{tp|p=27771772|t=2017. Reduced vascular amyloid burden at microhemorrhage sites in cerebral amyloid angiopathy |pdf=|usr=}}{{27771772}} gab.com Text Reduced vascular amyloid burden at microhemorrhage sites in cerebral amyloid angiopathy JO: Acta Neuropathol http://www.kidney.de/pget.php?&tw=1&pmid=27771772 #FOAvip Microhemorrhages are strongly associated with advanced cerebral amyloid angiopathy (CAA). Although it has been frequently proposed that the deposition of A? in the walls of cortical vessels directly causes microhemorrhages, this has not been studied in great detail, mainly because the ruptured vessels are often missed on routine histopathologic examination. Here, we examined histopathological data from studies targeting microhemorrhages with high-resolution ex vivo 7 T MRI in nine cases with moderate-to-severe CAA, and assessed the presence of A? in the walls of involved vessels. We also assessed the density of A? positive cortical vessels in areas surrounding microhemorrhages compared to control areas. In seven out of 19 microhemorrhages, the presumed involved vessel could be identified on the histopathological section. Only one of these vessels was positive for A? at the site of rupture. Moreover, the density of A? positive cortical vessels was lower (1.0 per mm2) within a range of 315 µm surrounding the microhemorrhage, compared to control areas (2.0 per mm2; p < 0.05). These findings question the widely held assumption that the deposition of A? in the walls of cortical vessels directly causes microhemorrhages.Electronic supplementary material: The online version of this article (doi:10.1007/s00401-016-1635-0) contains supplementary material, which is available to authorized users. Twit Text FOAVip Reduced vascular amyloid burden at microhemorrhage sites in cerebral amyloid angiopathy ????Acta Neuropathol http://www.kidney.de/pget.php?&tw=1&pmid=27771772 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27771772 #FOAvip English Wikipedia <ref>{{Cite pmid|27771772}}</ref> Reduced vascular amyloid burden at microhemorrhage sites in cerebral amyloid angiopathy #MMPMID27771772 van Veluw SJ; Kuijf HJ; Charidimou A; Viswanathan A; Biessels GJ; Rozemuller AJM; Frosch MP; Greenberg SM Acta Neuropathol 2017[]; 133 (3): 409-15 PMID27771772show ga Microhemorrhages are strongly associated with advanced cerebral amyloid angiopathy (CAA). Although it has been frequently proposed that the deposition of A? in the walls of cortical vessels directly causes microhemorrhages, this has not been studied in great detail, mainly because the ruptured vessels are often missed on routine histopathologic examination. Here, we examined histopathological data from studies targeting microhemorrhages with high-resolution ex vivo 7 T MRI in nine cases with moderate-to-severe CAA, and assessed the presence of A? in the walls of involved vessels. We also assessed the density of A? positive cortical vessels in areas surrounding microhemorrhages compared to control areas. In seven out of 19 microhemorrhages, the presumed involved vessel could be identified on the histopathological section. Only one of these vessels was positive for A? at the site of rupture. Moreover, the density of A? positive cortical vessels was lower (1.0 per mm2) within a range of 315 µm surrounding the microhemorrhage, compared to control areas (2.0 per mm2; p < 0.05). These findings question the widely held assumption that the deposition of A? in the walls of cortical vessels directly causes microhemorrhages.Electronic supplementary material: The online version of this article (doi:10.1007/s00401-016-1635-0) contains supplementary material, which is available to authorized users. äReduced vascular amyloid burden at microhemorrhage sites in cerebral a(epmc).pdf DeepDyve Pubget Overpricing