Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1016/j.bbagrm.2017.01.004 http://scihub22266oqcxt.onion/10.1016/j.bbagrm.2017.01.004 C5325806!5325806!28088440     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Biochim+Biophys+Acta 2017 ; 1860 (3): 349-62 Nephropedia Template TP {{tp|p=28088440|t=2017. Intersections of Post-Transcriptional Gene Regulatory Mechanisms with Intermediary Metabolism |pdf=|usr=}}{{28088440}} gab.com Text Intersections of Post-Transcriptional Gene Regulatory Mechanisms with Intermediary Metabolism JO: Biochim Biophys Acta http://www.kidney.de/pget.php?&tw=1&pmid=28088440 #FOAvip Intermediary metabolism studies have typically concentrated on four major regulatory mechanisms?substrate availability, allosteric enzyme regulation, post-translational enzyme modification, and regulated enzyme synthesis. Although transcriptional control has been a big focus, it is becoming increasingly evident that many post-transcriptional events are deeply embedded within the core regulatory circuits of enzyme synthesis/breakdown that maintain metabolic homeostasis. The prominent post-transcriptional mechanisms affecting intermediary metabolism include alternative pre-mRNA processing, mRNA stability and translation control, and the more recently discovered regulation by noncoding RNAs. In this review, we discuss the latest advances in our understanding of these diverse mechanisms at the cell-, tissue- and organismal-level. We also highlight the dynamics, complexity and non-linear nature of their regulatory roles in metabolic decision making, and deliberate some of the outstanding questions and challenges in this rapidly expanding field. Twit Text FOAVip Intersections of Post-Transcriptional Gene Regulatory Mechanisms with Intermediary Metabolism ????Biochim Biophys Acta http://www.kidney.de/pget.php?&tw=1&pmid=28088440 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28088440 #FOAvip English Wikipedia <ref>{{Cite pmid|28088440}}</ref> Intersections of Post-Transcriptional Gene Regulatory Mechanisms with Intermediary Metabolism #MMPMID28088440 Arif W; Datar G; Kalsotra A Biochim Biophys Acta 2017[Mar]; 1860 (3): 349-62 PMID28088440show ga Intermediary metabolism studies have typically concentrated on four major regulatory mechanisms?substrate availability, allosteric enzyme regulation, post-translational enzyme modification, and regulated enzyme synthesis. Although transcriptional control has been a big focus, it is becoming increasingly evident that many post-transcriptional events are deeply embedded within the core regulatory circuits of enzyme synthesis/breakdown that maintain metabolic homeostasis. The prominent post-transcriptional mechanisms affecting intermediary metabolism include alternative pre-mRNA processing, mRNA stability and translation control, and the more recently discovered regulation by noncoding RNAs. In this review, we discuss the latest advances in our understanding of these diverse mechanisms at the cell-, tissue- and organismal-level. We also highlight the dynamics, complexity and non-linear nature of their regulatory roles in metabolic decision making, and deliberate some of the outstanding questions and challenges in this rapidly expanding field. äIntersections of Post-Transcriptional Gene Regulatory Mechanisms with (epmc).pdf DeepDyve Pubget Overpricing