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10.1371/journal.pone.0171957 http://scihub22266oqcxt.onion/10.1371/journal.pone.0171957 C5325218!5325218!28234907     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       PLoS+One 2017 ; 12 (2): ä Nephropedia Template TP {{tp|p=28234907|t=2017. Novel form of miR-29b suppresses bleomycin-induced pulmonary fibrosis |pdf=|usr=}}{{28234907}} gab.com Text Novel form of miR-29b suppresses bleomycin-induced pulmonary fibrosis JO: PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=28234907 #FOAvip MicroRNA 29b (miR-29b) replacement therapy is effective for suppressing fibrosis in a mouse model. However, to develop clinical applications for miRNA mimics, the side effects of nucleic acid drugs have to be addressed. In this study, we focused on miRNA mimics in order to develop therapies for idiopathic pulmonary fibrosis. We developed a single-stranded RNA, termed ?miR-29b Psh-match,? that has a unique structure to avoid problems associated with the therapeutic uses of miRNAs. A comparison of miR-29b Psh-match and double-stranded one, termed ?miR-29b mimic? indicated that the single-stranded form was significantly effective towards fibrosis according to both in vivo and in vitro experiments. This novel form of miR-29b may become the foundation for developing an effective therapeutic drug for pulmonary fibrosis. Twit Text FOAVip Novel form of miR-29b suppresses bleomycin-induced pulmonary fibrosis ????PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=28234907 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28234907 #FOAvip English Wikipedia <ref>{{Cite pmid|28234907}}</ref> Novel form of miR-29b suppresses bleomycin-induced pulmonary fibrosis #MMPMID28234907 Yamada Y; Takanashi M; Sudo K; Ueda S; Ohno Si; Kuroda M PLoS One 2017[]; 12 (2): ä PMID28234907show ga MicroRNA 29b (miR-29b) replacement therapy is effective for suppressing fibrosis in a mouse model. However, to develop clinical applications for miRNA mimics, the side effects of nucleic acid drugs have to be addressed. In this study, we focused on miRNA mimics in order to develop therapies for idiopathic pulmonary fibrosis. We developed a single-stranded RNA, termed ?miR-29b Psh-match,? that has a unique structure to avoid problems associated with the therapeutic uses of miRNAs. A comparison of miR-29b Psh-match and double-stranded one, termed ?miR-29b mimic? indicated that the single-stranded form was significantly effective towards fibrosis according to both in vivo and in vitro experiments. This novel form of miR-29b may become the foundation for developing an effective therapeutic drug for pulmonary fibrosis. äNovel form of miR-29b suppresses bleomycin-induced pulmonary fibrosis (epmc).pdf DeepDyve Pubget Overpricing