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10.12688/f1000research.9399.1 http://scihub22266oqcxt.onion/10.12688/f1000research.9399.1 C5325071!5325071!28299186     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28299186&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       F1000Res 2017 ; 6 (ä): ä Nephropedia Template TP {{tp|p=28299186|t=2017. Recent advances in understanding and managing IgG4-related disease |pdf=|usr=}}{{28299186}} gab.com Text Recent advances in understanding and managing IgG4-related disease JO: F1000Res http://www.kidney.de/pget.php?&tw=1&pmid=28299186 #FOAvip IgG4-related disease was only recently discovered, so its description, management, and new discoveries related to its etiology are rapidly evolving. Because IgG4 itself is a unique antibody which is intimately related to the diagnosis of the disease, the role of plasmablasts in the pathophysiology remains an active area of discussion. Recent studies have uncovered a possible role for CD4-positive cytotoxic T lymphocytes, T follicular helper cells, and M2 macrophages. The clinical presentation is variable and can be vague, as this disease affects many organs and new presentations are continuing to be described. The diagnosis depends on clinical and histopathological assessment. The mainstay of treatment is with glucocorticoids, but rituximab has recently shown promise. Monitoring disease activity using imaging modalities (including positron emission tomography) and serum markers is imperative, as relapses are common. IgG4-related disease spans many medical disciplines but is a treatable condition with which all clinicians should be familiar. Twit Text FOAVip Recent advances in understanding and managing IgG4-related disease ????F1000Res http://www.kidney.de/pget.php?&tw=1&pmid=28299186 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28299186 #FOAvip English Wikipedia <ref>{{Cite pmid|28299186}}</ref> Recent advances in understanding and managing IgG4-related disease #MMPMID28299186 Wolfson AR; Hamilos DL F1000Res 2017[]; 6 (ä): ä PMID28299186show ga IgG4-related disease was only recently discovered, so its description, management, and new discoveries related to its etiology are rapidly evolving. Because IgG4 itself is a unique antibody which is intimately related to the diagnosis of the disease, the role of plasmablasts in the pathophysiology remains an active area of discussion. Recent studies have uncovered a possible role for CD4-positive cytotoxic T lymphocytes, T follicular helper cells, and M2 macrophages. The clinical presentation is variable and can be vague, as this disease affects many organs and new presentations are continuing to be described. The diagnosis depends on clinical and histopathological assessment. The mainstay of treatment is with glucocorticoids, but rituximab has recently shown promise. Monitoring disease activity using imaging modalities (including positron emission tomography) and serum markers is imperative, as relapses are common. IgG4-related disease spans many medical disciplines but is a treatable condition with which all clinicians should be familiar. äRecent advances in understanding and managing IgG4-related disease (epmc).pdf DeepDyve Pubget Overpricing