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10.12688/f1000research.9436.1 http://scihub22266oqcxt.onion/10.12688/f1000research.9436.1 C5325066!5325066!28299199     free     free     free       F1000Res 2017 ; 6 (ä): ä Nephropedia Template TP {{tp|p=28299199|t=2017. Advances in understanding hypopituitarism |pdf=|usr=}}{{28299199}} gab.com Text Advances in understanding hypopituitarism JO: F1000Res http://www.kidney.de/pget.php?&tw=1&pmid=28299199 #FOAvip The understanding of hypopituitarism has increased over the last three years. This review provides an overview of the most important recent findings. Most of the recent research in hypopituitarism has focused on genetics. New diagnostic techniques like next-generation sequencing have led to the description of different genetic mutations causative for congenital dysfunction of the pituitary gland while new molecular mechanisms underlying pituitary ontogenesis have also been described. Furthermore, hypopituitarism may occur because of an impairment of the distinctive vascularization of the pituitary gland, especially by disruption of the long vessel connection between the hypothalamus and the pituitary. Controversial findings have been published on post-traumatic hypopituitarism. Moreover, autoimmunity has been discussed in recent years as a possible reason for hypopituitarism. With the use of new drugs such as ipilimumab, hypopituitarism as a side effect of pharmaceuticals has come into focus. Besides new findings on the pathomechanism of hypopituitarism, there are new diagnostic tools in development, such as new growth hormone stimulants that are currently being tested in clinical trials. Moreover, cortisol measurement in scalp hair is a promising tool for monitoring cortisol levels over time. Twit Text FOAVip Advances in understanding hypopituitarism ????F1000Res http://www.kidney.de/pget.php?&tw=1&pmid=28299199 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28299199 #FOAvip English Wikipedia <ref>{{Cite pmid|28299199}}</ref> Advances in understanding hypopituitarism #MMPMID28299199 Stieg MR; Renner U; Stalla GK; Kopczak A F1000Res 2017[]; 6 (ä): ä PMID28299199show ga The understanding of hypopituitarism has increased over the last three years. This review provides an overview of the most important recent findings. Most of the recent research in hypopituitarism has focused on genetics. New diagnostic techniques like next-generation sequencing have led to the description of different genetic mutations causative for congenital dysfunction of the pituitary gland while new molecular mechanisms underlying pituitary ontogenesis have also been described. Furthermore, hypopituitarism may occur because of an impairment of the distinctive vascularization of the pituitary gland, especially by disruption of the long vessel connection between the hypothalamus and the pituitary. Controversial findings have been published on post-traumatic hypopituitarism. Moreover, autoimmunity has been discussed in recent years as a possible reason for hypopituitarism. With the use of new drugs such as ipilimumab, hypopituitarism as a side effect of pharmaceuticals has come into focus. Besides new findings on the pathomechanism of hypopituitarism, there are new diagnostic tools in development, such as new growth hormone stimulants that are currently being tested in clinical trials. Moreover, cortisol measurement in scalp hair is a promising tool for monitoring cortisol levels over time. äAdvances in understanding hypopituitarism (epmc).pdf DeepDyve Pubget Overpricing