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10.1186/s12882-017-0491-z http://scihub22266oqcxt.onion/10.1186/s12882-017-0491-z C5324214!5324214!28231769     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       BMC+Nephrol 2017 ; 18 (ä): ä Nephropedia Template TP {{tp|p=28231769|t=2017. Simple, readily available clinical indices predict early and late mortality among patients with ANCA-associated vasculitis |pdf=|usr=}}{{28231769}} gab.com Text Simple, readily available clinical indices predict early and late mortality among patients with ANCA-associated vasculitis JO: BMC Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=28231769 #FOAvip Background: The early identification of patients with ANCA-associated vasculitis (AAV) who are at increased risk for inferior clinical outcome at the time of diagnosis might help to optimize the immunosuppressive therapy. In this study we wanted to determine the predictive value of simple clinical characteristics, which may be applicable for early risk-stratification of patients with AAV. Methods: We retrospectively analyzed the outcome of 101 consecutive patients with AAV receiving a protocolized immunosuppressive therapy. Baseline Birmingham Vasculitis Activity Score (BVAS) and non-vasculitic comorbidities were computed, then predictors of early (<90 days) and late (>90 days) mortality, infectious death, relapse and end stage kidney disease (ESKD) were evaluated. Results: The baseline comorbidity score independently predicted early mortality (HR 1.622, CI 1.006?2.614), and showed association with infectious mortality (HR 2.056, CI 1.247?3.392). Patients with BVAS at or above median (=21) had worse early mortality in univariable analysis (HR 3.57, CI 1.039?12.243) (p?=?0.031), and had more frequent relapses (p?=?0.01) compared to patients with BVAS below median. Conclusions: Assessing baseline comorbidities, beside clinical indices characterizing the severity and extension of AAV, might help clinicians in risk-stratification of patients. Future prospective studies are needed to investigate whether therapies based on risk-stratification could improve both short term and long term survival. Twit Text FOAVip Simple, readily available clinical indices predict early and late mortality among patients with ANCA-associated vasculitis ????BMC Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=28231769 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28231769 #FOAvip English Wikipedia <ref>{{Cite pmid|28231769}}</ref> Simple, readily available clinical indices predict early and late mortality among patients with ANCA-associated vasculitis #MMPMID28231769 Haris Á; Polner K; Arányi J; Braunitzer H; Kaszás I; Rosivall L; Kökény G; Mucsi I BMC Nephrol 2017[]; 18 (ä): ä PMID28231769show ga Background: The early identification of patients with ANCA-associated vasculitis (AAV) who are at increased risk for inferior clinical outcome at the time of diagnosis might help to optimize the immunosuppressive therapy. In this study we wanted to determine the predictive value of simple clinical characteristics, which may be applicable for early risk-stratification of patients with AAV. Methods: We retrospectively analyzed the outcome of 101 consecutive patients with AAV receiving a protocolized immunosuppressive therapy. Baseline Birmingham Vasculitis Activity Score (BVAS) and non-vasculitic comorbidities were computed, then predictors of early (<90 days) and late (>90 days) mortality, infectious death, relapse and end stage kidney disease (ESKD) were evaluated. Results: The baseline comorbidity score independently predicted early mortality (HR 1.622, CI 1.006?2.614), and showed association with infectious mortality (HR 2.056, CI 1.247?3.392). Patients with BVAS at or above median (=21) had worse early mortality in univariable analysis (HR 3.57, CI 1.039?12.243) (p?=?0.031), and had more frequent relapses (p?=?0.01) compared to patients with BVAS below median. Conclusions: Assessing baseline comorbidities, beside clinical indices characterizing the severity and extension of AAV, might help clinicians in risk-stratification of patients. Future prospective studies are needed to investigate whether therapies based on risk-stratification could improve both short term and long term survival. äSimple, readily available clinical indices predict early and late mort(epmc).pdf DeepDyve Pubget Overpricing