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10.1038/srep43304 http://scihub22266oqcxt.onion/10.1038/srep43304 C5324107!5324107!28233825     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sci+Rep 2017 ; 7 (ä): ä Nephropedia Template TP {{tp|p=28233825|t=2017. Optical coherence tomography evaluation of pulmonary arterial vasculopathy in Systemic Sclerosis |pdf=|usr=}}{{28233825}} gab.com Text Optical coherence tomography evaluation of pulmonary arterial vasculopathy in Systemic Sclerosis JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=28233825 #FOAvip Our current understanding of the pathophysiology of pulmonary vascular disease is incomplete, since information about alterations of the pulmonary vasculature in pulmonary arterial hypertension (PAH) is primarily provided by autopsy or tissue specimens. The aim of this study was to compare the distal pulmonary vasculature of <2?mm in diameter in Systemic Sclerosis (SSc) patients with (n?=?17) and without (n?=?5) associated PAH using Optical Coherence Tomography during Right Heart catheterization. SSc-PAH patients showed significant thickening of Intima Media Thickening Area compared to patients without PAH (27 +/? 5.8% vs. 21 +/? 1.4%, p?=?0.024). A good haemodynamic response to previous targeted PAH treatment was associated with a significantly greater number of small pulmonary artery side branches <300??m per cm vessel (3.8 +/? 1.1 vs. 1.8 +/? 1.1; p?=?0.010) and not associated with Intima Media thickening Area (26 +/? 5.4% vs. 28 +/? 6.7%; p?=?0.6). Unexpected evidence of pulmonary artery thrombus formation was found in 19% of SSc-PAH patients. This is the first in-vivo study demonstrating a direct link between a structural abnormality of pulmonary arteries and a response to targeted treatment in PAH. Intravascular imaging may identify subgroups that may benefit from anticoagulation. Twit Text FOAVip Optical coherence tomography evaluation of pulmonary arterial vasculopathy in Systemic Sclerosis ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=28233825 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28233825 #FOAvip English Wikipedia <ref>{{Cite pmid|28233825}}</ref> Optical coherence tomography evaluation of pulmonary arterial vasculopathy in Systemic Sclerosis #MMPMID28233825 Schwaiger JP; Loder CD; Dobarro D; Kaier T; Reddecliffe S; Schreiber BE; Handler C; Denton CP; Coghlan JG Sci Rep 2017[]; 7 (ä): ä PMID28233825show ga Our current understanding of the pathophysiology of pulmonary vascular disease is incomplete, since information about alterations of the pulmonary vasculature in pulmonary arterial hypertension (PAH) is primarily provided by autopsy or tissue specimens. The aim of this study was to compare the distal pulmonary vasculature of <2?mm in diameter in Systemic Sclerosis (SSc) patients with (n?=?17) and without (n?=?5) associated PAH using Optical Coherence Tomography during Right Heart catheterization. SSc-PAH patients showed significant thickening of Intima Media Thickening Area compared to patients without PAH (27 +/? 5.8% vs. 21 +/? 1.4%, p?=?0.024). A good haemodynamic response to previous targeted PAH treatment was associated with a significantly greater number of small pulmonary artery side branches <300??m per cm vessel (3.8 +/? 1.1 vs. 1.8 +/? 1.1; p?=?0.010) and not associated with Intima Media thickening Area (26 +/? 5.4% vs. 28 +/? 6.7%; p?=?0.6). Unexpected evidence of pulmonary artery thrombus formation was found in 19% of SSc-PAH patients. This is the first in-vivo study demonstrating a direct link between a structural abnormality of pulmonary arteries and a response to targeted treatment in PAH. Intravascular imaging may identify subgroups that may benefit from anticoagulation. äOptical coherence tomography evaluation of pulmonary arterial vasculop(epmc).pdf DeepDyve Pubget Overpricing