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10.3389/fped.2017.00032 http://scihub22266oqcxt.onion/10.3389/fped.2017.00032 C5324021!5324021!28286744     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Front+Pediatr 2017 ; 5 (ä): ä Nephropedia Template TP {{tp|p=28286744|t=2017. Endocytic Trafficking at the Mature Podocyte Slit Diaphragm |pdf=|usr=}}{{28286744}} gab.com Text Endocytic Trafficking at the Mature Podocyte Slit Diaphragm JO: Front Pediatr http://www.kidney.de/pget.php?&tw=1&pmid=28286744 #FOAvip Endocytic trafficking couples cell signaling with the cytoskeletal dynamics by organizing a crosstalk between protein networks in different subcellular compartments. Proteins residing in the plasma membrane are internalized and transported as cargo in endocytic vesicles (i.e., endocytosis). Subsequently, cargo proteins can be delivered to lysosomes for degradation or recycled back to the plasma membrane. The slit diaphragm is a modified tight junction connecting foot processes of the glomerular epithelial cells, podocytes. Signaling at the slit diaphragm plays a critical role in the kidney while its dysfunction leads to glomerular protein loss (proteinuria), manifesting as nephrotic syndrome, a rare condition with an estimated incidence of 2?4 new cases per 100,000 each year. Relatively little is known about the role of endocytic trafficking in podocyte signaling and maintenance of the slit diaphragm integrity. This review will focus on the role of endocytic trafficking at the mature podocyte slit diaphragm. Twit Text FOAVip Endocytic Trafficking at the Mature Podocyte Slit Diaphragm ????Front Pediatr http://www.kidney.de/pget.php?&tw=1&pmid=28286744 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28286744 #FOAvip English Wikipedia <ref>{{Cite pmid|28286744}}</ref> Endocytic Trafficking at the Mature Podocyte Slit Diaphragm #MMPMID28286744 Swiatecka-Urban A Front Pediatr 2017[]; 5 (ä): ä PMID28286744show ga Endocytic trafficking couples cell signaling with the cytoskeletal dynamics by organizing a crosstalk between protein networks in different subcellular compartments. Proteins residing in the plasma membrane are internalized and transported as cargo in endocytic vesicles (i.e., endocytosis). Subsequently, cargo proteins can be delivered to lysosomes for degradation or recycled back to the plasma membrane. The slit diaphragm is a modified tight junction connecting foot processes of the glomerular epithelial cells, podocytes. Signaling at the slit diaphragm plays a critical role in the kidney while its dysfunction leads to glomerular protein loss (proteinuria), manifesting as nephrotic syndrome, a rare condition with an estimated incidence of 2?4 new cases per 100,000 each year. Relatively little is known about the role of endocytic trafficking in podocyte signaling and maintenance of the slit diaphragm integrity. This review will focus on the role of endocytic trafficking at the mature podocyte slit diaphragm. äEndocytic Trafficking at the Mature Podocyte Slit Diaphragm (epmc).pdf DeepDyve Pubget Overpricing