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10.18632/oncotarget.11411 http://scihub22266oqcxt.onion/10.18632/oncotarget.11411 C5323232!5323232!27556185     free     free     free       Oncotarget 2016 ; 7 (40): 66267-75 Nephropedia Template TP {{tp|p=27556185|t=2016. PinX1: structure, regulation and its functions in cancer |pdf=|usr=}}{{27556185}} gab.com Text PinX1: structure, regulation and its functions in cancer JO: Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=27556185 #FOAvip PIN2/TRF1-interacting telomerase inhibitor 1 (PinX1) is a novel cloned gene located at human chromosome 8p23, playing a vital role in maintaining telomeres length and chromosome stability. It has been demonstrated to be involved in tumor genesis and progression in most malignancies. However, some researches showed opposing molecular status of PinX1 gene and its expression patterns in several other types of tumors. The pathogenic mechanism of PinX1 expression in human malignancy is not yet clear. Moreover, emerging evidence suggest that PinX1 (especially its TID domain) might be a potential new target cancer treatment. Therefore, PinX1 may be a new potential diagnostic biomarker and therapeutic target for human cancers, and may play different roles in different human cancers. The functions and the mechanisms of PinX1 in various human cancers remain unclear, suggesting the necessity of further extensive works of its role in tumor genesis and progression. Twit Text FOAVip PinX1: structure, regulation and its functions in cancer ????Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=27556185 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27556185 #FOAvip English Wikipedia <ref>{{Cite pmid|27556185}}</ref> PinX1: structure, regulation and its functions in cancer #MMPMID27556185 Li HL; Song J; Yong HM; Hou PF; Chen YS; Song WB; Bai J; Zheng JN Oncotarget 2016[Oct]; 7 (40): 66267-75 PMID27556185show ga PIN2/TRF1-interacting telomerase inhibitor 1 (PinX1) is a novel cloned gene located at human chromosome 8p23, playing a vital role in maintaining telomeres length and chromosome stability. It has been demonstrated to be involved in tumor genesis and progression in most malignancies. However, some researches showed opposing molecular status of PinX1 gene and its expression patterns in several other types of tumors. The pathogenic mechanism of PinX1 expression in human malignancy is not yet clear. Moreover, emerging evidence suggest that PinX1 (especially its TID domain) might be a potential new target cancer treatment. Therefore, PinX1 may be a new potential diagnostic biomarker and therapeutic target for human cancers, and may play different roles in different human cancers. The functions and the mechanisms of PinX1 in various human cancers remain unclear, suggesting the necessity of further extensive works of its role in tumor genesis and progression. äPinX1: structure, regulation and its functions in cancer (epmc).pdf DeepDyve Pubget Overpricing