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10.2147/IJGM.S127689 http://scihub22266oqcxt.onion/10.2147/IJGM.S127689 C5322849!5322849!28255252     free     free     free       Int+J+Gen+Med 2017 ; 10 (ä): 39-52 Nephropedia Template TP {{tp|p=28255252|t=2017. Hepatitis C treatment: where are we now?|pdf=|usr=}}{{28255252}} gab.com Text Hepatitis C treatment: where are we now JO: Int J Gen Med http://www.kidney.de/pget.php?&tw=1&pmid=28255252 #FOAvip Chronic hepatitis C infection affects millions of people worldwide and confers significant morbidity and mortality. Effective treatment is needed to prevent disease progression and associated complications. Previous treatment options were limited to interferon and ribavirin (RBV) regimens, which gave low cure rates and were associated with unpleasant side effects. The era of direct-acting antiviral (DAA) therapies began with the development of first-generation NS3/4A protease inhibitors in 2011. They vastly improved outcomes for patients, particularly those with genotype 1 infection, the most prevalent genotype globally. Since then, a multitude of DAAs have been licensed for use, and outcomes for patients have improved further, with fewer side effects and cure rates approaching 100%. Recent regimens are interferon-free, and in many cases, RBV-free, and involve a combination of DAA agents. This review summarizes the treatment options currently available and discusses potential barriers that may delay the global eradication of hepatitis C. Twit Text FOAVip Hepatitis C treatment: where are we now ????Int J Gen Med http://www.kidney.de/pget.php?&tw=1&pmid=28255252 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28255252 #FOAvip English Wikipedia <ref>{{Cite pmid|28255252}}</ref> Hepatitis C treatment: where are we now? #MMPMID28255252 Burstow NJ; Mohamed Z; Gomaa AI; Sonderup MW; Cook NA; Waked I; Spearman CW; Taylor-Robinson SD Int J Gen Med 2017[]; 10 (ä): 39-52 PMID28255252show ga Chronic hepatitis C infection affects millions of people worldwide and confers significant morbidity and mortality. Effective treatment is needed to prevent disease progression and associated complications. Previous treatment options were limited to interferon and ribavirin (RBV) regimens, which gave low cure rates and were associated with unpleasant side effects. The era of direct-acting antiviral (DAA) therapies began with the development of first-generation NS3/4A protease inhibitors in 2011. They vastly improved outcomes for patients, particularly those with genotype 1 infection, the most prevalent genotype globally. Since then, a multitude of DAAs have been licensed for use, and outcomes for patients have improved further, with fewer side effects and cure rates approaching 100%. Recent regimens are interferon-free, and in many cases, RBV-free, and involve a combination of DAA agents. This review summarizes the treatment options currently available and discusses potential barriers that may delay the global eradication of hepatitis C. äHepatitis C treatment: where are we now?(epmc).pdf DeepDyve Pubget Overpricing