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10.1007/s00441-016-2534-3 http://scihub22266oqcxt.onion/10.1007/s00441-016-2534-3 C5320021!5320021!27917436     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cell+Tissue+Res 2017 ; 367 (3): 457-68 Nephropedia Template TP {{tp|p=27917436|t=2017. Looking ahead: where to next for animal models of bronchopulmonary dysplasia?|pdf=|usr=}}{{27917436}} gab.com Text Looking ahead: where to next for animal models of bronchopulmonary dysplasia JO: Cell Tissue Res http://www.kidney.de/pget.php?&tw=1&pmid=27917436 #FOAvip Bronchopulmonary dysplasia (BPD) is the most common complication of preterm birth, with appreciable morbidity and mortality in a neonatal intensive care setting. Much interest has been shown in the identification of pathogenic pathways that are amenable to pharmacological manipulation (1) to facilitate the development of novel therapeutic and medical management strategies and (2) to identify the basic mechanisms of late lung development, which remains poorly understood. A number of animal models have therefore been developed and continue to be refined with the aim of recapitulating pathological pulmonary hallmarks noted in lungs from neonates with BPD. These animal models rely on several injurious stimuli, such as mechanical ventilation or oxygen toxicity and infection and sterile inflammation, as applied in mice, rats, rabbits, pigs, lambs and nonhuman primates. This review addresses recent developments in modeling BPD in experimental animals and highlights important neglected areas that demand attention. Additionally, recent progress in the quantitative microscopic analysis of pathology tissue is described, together with new in vitro approaches of value for the study of normal and aberrant alveolarization. The need to examine long-term sequelae of damage to the developing neonatal lung is also considered, as is the need to move beyond the study of the lungs alone in experimental animal models of BPD. Twit Text FOAVip Looking ahead: where to next for animal models of bronchopulmonary dysplasia ????Cell Tissue Res http://www.kidney.de/pget.php?&tw=1&pmid=27917436 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27917436 #FOAvip English Wikipedia <ref>{{Cite pmid|27917436}}</ref> Looking ahead: where to next for animal models of bronchopulmonary dysplasia? #MMPMID27917436 Nardiello C; Mi?íková I; Morty RE Cell Tissue Res 2017[]; 367 (3): 457-68 PMID27917436show ga Bronchopulmonary dysplasia (BPD) is the most common complication of preterm birth, with appreciable morbidity and mortality in a neonatal intensive care setting. Much interest has been shown in the identification of pathogenic pathways that are amenable to pharmacological manipulation (1) to facilitate the development of novel therapeutic and medical management strategies and (2) to identify the basic mechanisms of late lung development, which remains poorly understood. A number of animal models have therefore been developed and continue to be refined with the aim of recapitulating pathological pulmonary hallmarks noted in lungs from neonates with BPD. These animal models rely on several injurious stimuli, such as mechanical ventilation or oxygen toxicity and infection and sterile inflammation, as applied in mice, rats, rabbits, pigs, lambs and nonhuman primates. This review addresses recent developments in modeling BPD in experimental animals and highlights important neglected areas that demand attention. Additionally, recent progress in the quantitative microscopic analysis of pathology tissue is described, together with new in vitro approaches of value for the study of normal and aberrant alveolarization. The need to examine long-term sequelae of damage to the developing neonatal lung is also considered, as is the need to move beyond the study of the lungs alone in experimental animal models of BPD. äLooking ahead: where to next for animal models of bronchopulmonary dys(epmc).pdf DeepDyve Pubget Overpricing