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2017 ; 5
(ä): 27
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The Epidemiology of Chronic Suppurative Lung Disease and Bronchiectasis in
Children and Adolescents
#MMPMID28265556
McCallum GB
; Binks MJ
Front Pediatr
2017[]; 5
(ä): 27
PMID28265556
show ga
In the modern era, the global burden of childhood chronic suppurative lung
disease (CSLD) remains poorly captured by the literature. What is clear, however,
is that CSLD is essentially a disease of poverty. Disadvantaged children from
indigenous and low- and middle-income populations had a substantially higher
burden of CSLD, generally infectious in etiology and of a more severe nature,
than children in high-income countries. A universal issue was the delay in
diagnosis and the inconsistent reporting of clinical features. Importantly,
infection-related CSLD is largely preventable. A considerable research and
clinical effort is needed to identify modifiable risk factors and socioeconomic
determinants of CSLD and provide robust evidence to guide optimal prevention and
management strategies. The purpose of this review was to update the international
literature on the epidemiology, etiology, and clinical features of pediatric
CSLD.