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10.1016/j.cyto.2016.11.017

http://scihub22266oqcxt.onion/10.1016/j.cyto.2016.11.017
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C5316352!5316352!27940089
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suck abstract from ncbi


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pmid27940089      Cytokine 2017 ; 91 (ä): 10-2
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  • The ancient cytokine IL-17D is regulated by Nrf2 and mediates tumor and virus surveillance #MMPMID27940089
  • Seelige R; Washington A; Bui JD
  • Cytokine 2017[Mar]; 91 (ä): 10-2 PMID27940089show ga
  • Early stage immune responses can dictate the severity and outcome of inflammatory processes such as tumor growth and viral infection. Cytokines such as the interleukin 17 (IL-17) family and cellular stress defense (e.g., anti-oxidant) pathways have evolved early and regulate disease surveillance in vertebrates and invertebrates as far back as Caenorhabditis elegans. Our group has recently found a new role for nuclear factor erythroid-derived 2-like 2 (Nrf2) in regulating early anti-cancer immune responses by inducing IL-17D and recruiting natural killer (NK) cells. In this Cytokine Stimulus, we discuss recent findings that encourage boosting the Nrf2/IL-17D/NK cell axis for the treatment of cancer and viral infection.
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