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10.1371/journal.pone.0171881 http://scihub22266oqcxt.onion/10.1371/journal.pone.0171881 C5315394!5315394!28212424     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       PLoS+One 2017 ; 12 (2): ä Nephropedia Template TP {{tp|p=28212424|t=2017. Risk factors for central nervous system tumors in children: New findings from a case-control study |pdf=|usr=}}{{28212424}} gab.com Text Risk factors for central nervous system tumors in children: New findings from a case-control study JO: PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=28212424 #FOAvip Background: Central nervous system tumors (CNS) are the most frequent solid tumor in children. Causes of CNS tumors are mainly unknown and only 5% of the cases can be explained by genetic predisposition. We studied the effects of environmental exposure on the incidence of CNS tumors in children by subtype, according to exposure to industrial and/or urban environment, exposure to crops and according to socio-economic status of the child. Methods: We carried out a population-based case-control study of CNS tumors in Spain, covering 714 incident cases collected from the Spanish Registry of Childhood Tumors (period 1996?2011) and 4284 controls, individually matched by year of birth, sex, and autonomous region of residence. We built a covariate to approximate the exposure to industrial and/or urban environment and a covariate for the exposure to crops (GCI) using the coordinates of the home addresses of the children. We used the 2001 Census to obtain information about socio-economic status (SES). We fitted logistic regression models to estimate odds ratios (ORs) and 95% confidence intervals (95%CIs). Results: The results for all CNS tumors showed an excess risk (OR = 1.37; 95%CI = 1.09?1.73) for SES, i.e., children living in the least deprived areas had 37% more risk of CNS tumor than children living in the most deprived areas. For GCI, an increase of 10% in crop surface in the 1-km buffer around the residence implied an increase of 22% in the OR (OR = 1.22; 95%CI = 1.15?1.29). Children living in the intersection of industrial and urban areas could have a greater risk of CNS tumors than children who live outside these areas (OR = 1.20; 95%CI = 0.82?1.77). Living in urban areas (OR = 0.90; 95%CI = 0.65?1.24) or industrial areas (OR = 0.96; 95%CI = 0.81?1.77) did not seem to increase the risk for all CNS tumors together. By subtype, Astrocytomas, Intracranial and intraspinal embryonal tumors, and other gliomas showed similar results. Conclusion: Our results suggest that higher socioeconomic status and exposure to crops could increase the risk of CNS tumors in children. Twit Text FOAVip Risk factors for central nervous system tumors in children: New findings from a case-control study ????PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=28212424 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28212424 #FOAvip English Wikipedia <ref>{{Cite pmid|28212424}}</ref> Risk factors for central nervous system tumors in children: New findings from a case-control study #MMPMID28212424 Ramis R; Tamayo-Uria I; Gómez-Barroso D; López-Abente G; Morales-Piga A; Pardo Romaguera E; Aragonés N; García-Pérez J PLoS One 2017[]; 12 (2): ä PMID28212424show ga Background: Central nervous system tumors (CNS) are the most frequent solid tumor in children. Causes of CNS tumors are mainly unknown and only 5% of the cases can be explained by genetic predisposition. We studied the effects of environmental exposure on the incidence of CNS tumors in children by subtype, according to exposure to industrial and/or urban environment, exposure to crops and according to socio-economic status of the child. Methods: We carried out a population-based case-control study of CNS tumors in Spain, covering 714 incident cases collected from the Spanish Registry of Childhood Tumors (period 1996?2011) and 4284 controls, individually matched by year of birth, sex, and autonomous region of residence. We built a covariate to approximate the exposure to industrial and/or urban environment and a covariate for the exposure to crops (GCI) using the coordinates of the home addresses of the children. We used the 2001 Census to obtain information about socio-economic status (SES). We fitted logistic regression models to estimate odds ratios (ORs) and 95% confidence intervals (95%CIs). Results: The results for all CNS tumors showed an excess risk (OR = 1.37; 95%CI = 1.09?1.73) for SES, i.e., children living in the least deprived areas had 37% more risk of CNS tumor than children living in the most deprived areas. For GCI, an increase of 10% in crop surface in the 1-km buffer around the residence implied an increase of 22% in the OR (OR = 1.22; 95%CI = 1.15?1.29). Children living in the intersection of industrial and urban areas could have a greater risk of CNS tumors than children who live outside these areas (OR = 1.20; 95%CI = 0.82?1.77). Living in urban areas (OR = 0.90; 95%CI = 0.65?1.24) or industrial areas (OR = 0.96; 95%CI = 0.81?1.77) did not seem to increase the risk for all CNS tumors together. By subtype, Astrocytomas, Intracranial and intraspinal embryonal tumors, and other gliomas showed similar results. Conclusion: Our results suggest that higher socioeconomic status and exposure to crops could increase the risk of CNS tumors in children. äRisk factors for central nervous system tumors in children: New findin(epmc).pdf DeepDyve Pubget Overpricing