Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28255544
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28255544
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 World+J+Clin+Cases
2017 ; 5
(2
): 27-34
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Externalized conductors and insulation failure in Biotronik defibrillator leads:
History repeating or a false alarm?
#MMPMID28255544
De Maria E
; Borghi A
; Bonetti L
; Fontana PL
; Cappelli S
World J Clin Cases
2017[Feb]; 5
(2
): 27-34
PMID28255544
show ga
Conductor externalization and insulation failure are frequent complications with
the recalled St. Jude Medical Riata implantable cardioverter-defibrillator (ICD)
leads. Conductor externalization is a "unique" failure mechanism: Cables
externalize through the insulation ("inside-out" abrasion) and appear outside the
lead body. Recently, single reports described a similar failure also for
Biotronik leads. Moreover, some studies reported a high rate of electrical
dysfunction (not only insulation failure) with Biotronik Linox leads and a
reduced survival rate in comparison with the competitors. In this paper we
describe the case of a patient with a Biotronik Kentrox ICD lead presenting with
signs of insulation failure and conductor externalization at fluoroscopy. Due to
the high risk of extraction we decided to implant a new lead, abandoning the
damaged one; lead reimplant was uneventful. Subsequently, we review currently
available literature about Biotronik Kentrox and Linox ICD lead failure and in
particular externalized conductors. Some single-center studies and a
non-prospective registry reported a survival rate between 88% and 91% at 5 years
for Linox leads, significantly worse than that of other manufacturers. However,
the preliminary results of two ongoing multicenter, prospective registries
(GALAXY and CELESTIAL) showed 96% survival rate at 5 years after implant, well
within industry standards. Ongoing data collection is needed to confirm
longer-term performance of this family of ICD leads.
free
free
free
