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10.1098/rsfs.2016.0100 http://scihub22266oqcxt.onion/10.1098/rsfs.2016.0100 C5311903!5311903!28382199     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Interface+Focus 2017 ; 7 (2): ä Nephropedia Template TP {{tp|p=28382199|t=2017. Mitochondrial metabolites: undercover signalling molecules |pdf=|usr=}}{{28382199}} gab.com Text Mitochondrial metabolites: undercover signalling molecules JO: Interface Focus http://www.kidney.de/pget.php?&tw=1&pmid=28382199 #FOAvip Mitochondria are one of most characterized metabolic hubs of the cell. Here, crucial biochemical reactions occur and most of the cellular adenosine triphosphate (ATP) is produced. In addition, mitochondria act as signalling platforms and communicate with the rest of the cell by modulating calcium fluxes, by producing free radicals, and by releasing bioactive proteins. It is emerging that mitochondrial metabolites can also act as second messengers and can elicit profound (epi)genetic changes. This review describes the many signalling functions of mitochondrial metabolites under normal and stress conditions, focusing on metabolites of the tricarboxylic acid cycle. We provide a new framework for understanding the role of mitochondrial metabolism in cellular pathophysiology. Twit Text FOAVip Mitochondrial metabolites: undercover signalling molecules ????Interface Focus http://www.kidney.de/pget.php?&tw=1&pmid=28382199 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28382199 #FOAvip English Wikipedia <ref>{{Cite pmid|28382199}}</ref> Mitochondrial metabolites: undercover signalling molecules #MMPMID28382199 Frezza C Interface Focus 2017[Apr]; 7 (2): ä PMID28382199show ga Mitochondria are one of most characterized metabolic hubs of the cell. Here, crucial biochemical reactions occur and most of the cellular adenosine triphosphate (ATP) is produced. In addition, mitochondria act as signalling platforms and communicate with the rest of the cell by modulating calcium fluxes, by producing free radicals, and by releasing bioactive proteins. It is emerging that mitochondrial metabolites can also act as second messengers and can elicit profound (epi)genetic changes. This review describes the many signalling functions of mitochondrial metabolites under normal and stress conditions, focusing on metabolites of the tricarboxylic acid cycle. We provide a new framework for understanding the role of mitochondrial metabolism in cellular pathophysiology. äMitochondrial metabolites: undercover signalling molecules (epmc).pdf DeepDyve Pubget Overpricing