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10.3389/fped.2017.00019 http://scihub22266oqcxt.onion/10.3389/fped.2017.00019 C5309219!5309219!28261574     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Front+Pediatr 2017 ; 5 (ä): ä Nephropedia Template TP {{tp|p=28261574|t=2017. Persistent and Recurrent Bacterial Bronchitis?A Paradigm Shift in Our Understanding of Chronic Respiratory Disease |pdf=|usr=}}{{28261574}} gab.com Text Persistent and Recurrent Bacterial Bronchitis A Paradigm Shift in Our Understanding of Chronic Respiratory Disease JO: Front Pediatr http://www.kidney.de/pget.php?&tw=1&pmid=28261574 #FOAvip The recent recognition that the conducting airways are not ?sterile? and that they have their own dynamic microbiome, together with the rapid advances in our understanding of microbial biofilms and their roles in the causation of respiratory diseases (such as chronic bronchitis, sinusitis, and chronic otitis media), permit us to update the ?vicious circle? hypothesis of the causation of bronchiectasis. This proposes that chronic inflammation driven by persistent bacterial bronchitis (PBB) causes damage to both the epithelium, resulting in impaired mucociliary clearance, and to the airway wall, which eventually manifests as bronchiectasis. The link between a ?chronic bronchitis? and a persistence of bacterial pathogens, such as non-typable Haemophilus influenzae, was first made more than 100?years ago, and its probable role in the causation of bronchiectasis was proposed soon afterward. The recognition that the ?usual suspects? are adept at forming biofilms and hence are able to persist and dominate the normal dynamically changing ?healthy microbiome? of the conducting airways provides an explanation for the chronic colonization of the bronchi and for the associated chronic neutrophil-dominated inflammation characteristic of a PBB. Understanding the complex interaction between the host and the microbial communities of the conducting airways in health and disease will be a key component in optimizing pulmonary health in the future. Twit Text FOAVip Persistent and Recurrent Bacterial Bronchitis A Paradigm Shift in Our Understanding of Chronic Respiratory Disease ????Front Pediatr http://www.kidney.de/pget.php?&tw=1&pmid=28261574 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28261574 #FOAvip English Wikipedia <ref>{{Cite pmid|28261574}}</ref> Persistent and Recurrent Bacterial Bronchitis?A Paradigm Shift in Our Understanding of Chronic Respiratory Disease #MMPMID28261574 Ishak A; Everard ML Front Pediatr 2017[]; 5 (ä): ä PMID28261574show ga The recent recognition that the conducting airways are not ?sterile? and that they have their own dynamic microbiome, together with the rapid advances in our understanding of microbial biofilms and their roles in the causation of respiratory diseases (such as chronic bronchitis, sinusitis, and chronic otitis media), permit us to update the ?vicious circle? hypothesis of the causation of bronchiectasis. This proposes that chronic inflammation driven by persistent bacterial bronchitis (PBB) causes damage to both the epithelium, resulting in impaired mucociliary clearance, and to the airway wall, which eventually manifests as bronchiectasis. The link between a ?chronic bronchitis? and a persistence of bacterial pathogens, such as non-typable Haemophilus influenzae, was first made more than 100?years ago, and its probable role in the causation of bronchiectasis was proposed soon afterward. The recognition that the ?usual suspects? are adept at forming biofilms and hence are able to persist and dominate the normal dynamically changing ?healthy microbiome? of the conducting airways provides an explanation for the chronic colonization of the bronchi and for the associated chronic neutrophil-dominated inflammation characteristic of a PBB. Understanding the complex interaction between the host and the microbial communities of the conducting airways in health and disease will be a key component in optimizing pulmonary health in the future. äPersistent and Recurrent Bacterial Bronchitis?A Paradigm Shift in Our (epmc).pdf DeepDyve Pubget Overpricing