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10.18632/oncotarget.11755 http://scihub22266oqcxt.onion/10.18632/oncotarget.11755 C5308624!5308624!27590513     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27590513&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Oncotarget 2016 ; 7 (38): 60896-905 Nephropedia Template TP {{tp|p=27590513|t=2016. Activation and selective IL-17 response of human V?9V?2 T lymphocytes by TLR-activated plasmacytoid dendritic cells |pdf=|usr=}}{{27590513}} gab.com Text Activation and selective IL-17 response of human V 9V 2 T lymphocytes by TLR-activated plasmacytoid dendritic cells JO: Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=27590513 #FOAvip V?9V?2 T cells and plasmacytoid dendritic cells (pDCs) are two distinct cell types of innate immunity that participate in early phases of immune response. We investigated whether a close functional relationship exists between these two cell populations using an in vitro co-culture in a human system.pDCs that had been activated by IL-3 and the TLR9 ligand CpG induced substantial activation of V?9V?2 T cells upon co-culture, which was cell-to-cell contact dependent, as demonstrated in transwell experiments, but that did not involve any of the costimulatory molecules potentially expressed by pDCs or V?9V2 T cells, such as ICOS-L, OX40 and CD40L. Activated pDCs selectively induced IL-17, but not IFN-?, responses of V?9V?2T cells, which was dominant over the antigen-induced response, and this was associated with the expansion of memory (both central and effector memory) subsets of V?9V?2 T cells.Overall, our results provide a further piece of information on the complex relationship between these two populations of cells with innate immunity features during inflammatory responses. Twit Text FOAVip Activation and selective IL-17 response of human V 9V 2 T lymphocytes by TLR-activated plasmacytoid dendritic cells ????Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=27590513 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27590513 #FOAvip English Wikipedia <ref>{{Cite pmid|27590513}}</ref> Activation and selective IL-17 response of human V?9V?2 T lymphocytes by TLR-activated plasmacytoid dendritic cells #MMPMID27590513 Presti EL; Caccamo N; Orlando V; Dieli F; Meraviglia S Oncotarget 2016[Sep]; 7 (38): 60896-905 PMID27590513show ga V?9V?2 T cells and plasmacytoid dendritic cells (pDCs) are two distinct cell types of innate immunity that participate in early phases of immune response. We investigated whether a close functional relationship exists between these two cell populations using an in vitro co-culture in a human system.pDCs that had been activated by IL-3 and the TLR9 ligand CpG induced substantial activation of V?9V?2 T cells upon co-culture, which was cell-to-cell contact dependent, as demonstrated in transwell experiments, but that did not involve any of the costimulatory molecules potentially expressed by pDCs or V?9V2 T cells, such as ICOS-L, OX40 and CD40L. Activated pDCs selectively induced IL-17, but not IFN-?, responses of V?9V?2T cells, which was dominant over the antigen-induced response, and this was associated with the expansion of memory (both central and effector memory) subsets of V?9V?2 T cells.Overall, our results provide a further piece of information on the complex relationship between these two populations of cells with innate immunity features during inflammatory responses. äActivation and selective IL-17 response of human V?9V?2 T lymphocytes (epmc).pdf DeepDyve Pubget Overpricing