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10.18632/oncotarget.11755 http://scihub22266oqcxt.onion/10.18632/oncotarget.11755 C5308624!5308624 !27590513     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27590513 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Oncotarget 2016 ; 7 (38 ): 60896-60905 Nephropedia Template TP {{tp|p=27590513 |t=2016. Activation and selective IL-17 response of human V?9V?2 T lymphocytes by TLR-activated plasmacytoid dendritic cells |pdf=|usr=}}{{27590513 }} gab.com Text Activation and selective IL-17 response of human V 9V 2 T lymphocytes by TLR-activated plasmacytoid dendritic cells JO: Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=27590513 #FOAvip V?9V?2 T cells and plasmacytoid dendritic cells (pDCs) are two distinct cell types of innate immunity that participate in early phases of immune response. We investigated whether a close functional relationship exists between these two cell populations using an in vitro co-culture in a human system.pDCs that had been activated by IL-3 and the TLR9 ligand CpG induced substantial activation of V?9V?2 T cells upon co-culture, which was cell-to-cell contact dependent, as demonstrated in transwell experiments, but that did not involve any of the costimulatory molecules potentially expressed by pDCs or V?9V2 T cells, such as ICOS-L, OX40 and CD40L. Activated pDCs selectively induced IL-17, but not IFN-?, responses of V?9V?2T cells, which was dominant over the antigen-induced response, and this was associated with the expansion of memory (both central and effector memory) subsets of V?9V?2 T cells.Overall, our results provide a further piece of information on the complex relationship between these two populations of cells with innate immunity features during inflammatory responses. Twit Text FOAVip Activation and selective IL-17 response of human V 9V 2 T lymphocytes by TLR-activated plasmacytoid dendritic cells ????Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=27590513 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27590513 #FOAvip English Wikipedia <ref>{{Cite pmid|27590513 }}</ref> Activation and selective IL-17 response of human V?9V?2 T lymphocytes by TLR-activated plasmacytoid dendritic cells #MMPMID27590513 Lo Presti E ; Caccamo N ; Orlando V ; Dieli F ; Meraviglia S Oncotarget 2016[Sep]; 7 (38 ): 60896-60905 PMID27590513 show ga V?9V?2 T cells and plasmacytoid dendritic cells (pDCs) are two distinct cell types of innate immunity that participate in early phases of immune response. We investigated whether a close functional relationship exists between these two cell populations using an in vitro co-culture in a human system.pDCs that had been activated by IL-3 and the TLR9 ligand CpG induced substantial activation of V?9V?2 T cells upon co-culture, which was cell-to-cell contact dependent, as demonstrated in transwell experiments, but that did not involve any of the costimulatory molecules potentially expressed by pDCs or V?9V2 T cells, such as ICOS-L, OX40 and CD40L. Activated pDCs selectively induced IL-17, but not IFN-?, responses of V?9V?2T cells, which was dominant over the antigen-induced response, and this was associated with the expansion of memory (both central and effector memory) subsets of V?9V?2 T cells.Overall, our results provide a further piece of information on the complex relationship between these two populations of cells with innate immunity features during inflammatory responses. |Antigen Presentation [MESH] |CD40 Ligand/metabolism [MESH] |Cell Communication [MESH] |Cell Proliferation [MESH] |Coculture Techniques [MESH] |CpG Islands [MESH] |Dendritic Cells/*immunology [MESH] |Humans [MESH] |Immunity, Innate [MESH] |Immunologic Memory [MESH] |Inducible T-Cell Co-Stimulator Ligand/metabolism [MESH] |Interferon-gamma/metabolism [MESH] |Interleukin-17/*metabolism [MESH] |Leukocytes, Mononuclear/cytology [MESH] |Ligands [MESH] |Lymphocyte Activation/*immunology [MESH] |Phenotype [MESH] |Receptors, OX40/metabolism [MESH]Activation and selective IL-17 response of human V?9V?2 T lymphocytes (epmc).pdf DeepDyve Pubget Overpricing