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10.3389/fcell.2017.00009 http://scihub22266oqcxt.onion/10.3389/fcell.2017.00009 C5306212!5306212!28261581     free     free     free       Front+Cell+Dev+Biol 2017 ; 5 (ä): ä Nephropedia Template TP {{tp|p=28261581|t=2017. PBX1 as Pioneer Factor: A Case Still Open |pdf=|usr=}}{{28261581}} gab.com Text PBX1 as Pioneer Factor: A Case Still Open JO: Front Cell Dev Biol http://www.kidney.de/pget.php?&tw=1&pmid=28261581 #FOAvip Pioneer factors are proteins that can recognize their target sites in barely accessible chromatin and initiate a cascade of events that allows for later transcriptional activation of the respective genes. Pioneer factors are therefore particularly well-suited to initiate cell fate changes. To date, only a small number of pioneer factors have been identified and studied in depth, such as FOXD3/FOXA1, OCT4, or SOX2. Interestingly, several recent studies reported that the PBC transcription factor PBX1 can access transcriptionally inactive genomic loci. Here, we summarize the evidence linking PBX1 with transcriptional pioneer functions, suggest potential mechanisms involved and discuss open questions to be resolved. Twit Text FOAVip PBX1 as Pioneer Factor: A Case Still Open ????Front Cell Dev Biol http://www.kidney.de/pget.php?&tw=1&pmid=28261581 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28261581 #FOAvip English Wikipedia <ref>{{Cite pmid|28261581}}</ref> PBX1 as Pioneer Factor: A Case Still Open #MMPMID28261581 Grebbin BM; Schulte D Front Cell Dev Biol 2017[]; 5 (ä): ä PMID28261581show ga Pioneer factors are proteins that can recognize their target sites in barely accessible chromatin and initiate a cascade of events that allows for later transcriptional activation of the respective genes. Pioneer factors are therefore particularly well-suited to initiate cell fate changes. To date, only a small number of pioneer factors have been identified and studied in depth, such as FOXD3/FOXA1, OCT4, or SOX2. Interestingly, several recent studies reported that the PBC transcription factor PBX1 can access transcriptionally inactive genomic loci. Here, we summarize the evidence linking PBX1 with transcriptional pioneer functions, suggest potential mechanisms involved and discuss open questions to be resolved. äPBX1 as Pioneer Factor: A Case Still Open (epmc).pdf DeepDyve Pubget Overpricing