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10.1091/mbc.E16-10-0698

http://scihub22266oqcxt.onion/10.1091/mbc.E16-10-0698
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C5305259!5305259!27974639
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suck abstract from ncbi


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pmid27974639      Mol+Biol+Cell 2017 ; 28 (4): 524-34
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  • Visualizing the dynamic coupling of claudin strands to the actin cytoskeleton through ZO-1 #MMPMID27974639
  • Van Itallie CM; Tietgens AJ; Anderson JM
  • Mol Biol Cell 2017[Feb]; 28 (4): 524-34 PMID27974639show ga
  • GFP claudins (cldns) make dynamic strand patches between fibroblasts regulated by ZO-1 binding. Independent of ZO-1, cldn strands break and reanneal; new cldns are preferentially incorporated into break sites. Intermittent tethering of cldns to actin is speculated to allow the paracellular seal to accommodate physiological changes in cell shape.
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