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10.1002/cpt.442

http://scihub22266oqcxt.onion/10.1002/cpt.442
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C5305120!5305120!27506881
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suck abstract from ncbi


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pmid27506881      Clin+Pharmacol+Ther 2016 ; 100 (5): 489-99
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  • The Plasma Membrane Monoamine Transporter (PMAT): Structure, Function, and Role in Organic Cation Disposition #MMPMID27506881
  • Wang J
  • Clin Pharmacol Ther 2016[Nov]; 100 (5): 489-99 PMID27506881show ga
  • Plasma membrane monoamine transporter (PMAT) is a new polyspecific organic cation transporter that transports a variety of biogenic amines and xenobiotic cations. Highly expressed in the brain, PMAT represents a major uptake2 transporter for monoamine neurotransmitters. At the blood?cerebrospinal fluid (CSF) barrier, PMAT is the principal organic cation transporter for removing neurotoxins and drugs from the CSF. Here I summarize our latest understanding of PMAT and its roles in monoamine uptake and xenobiotic disposition.
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