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10.1073/pnas.1615973114 http://scihub22266oqcxt.onion/10.1073/pnas.1615973114 C5293035!5293035!28096423     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Proc+Natl+Acad+Sci+U+S+A 2017 ; 114 (5): 1111-6 Nephropedia Template TP {{tp|p=28096423|t=2017. Trogocytosis of peptide?MHC class II complexes from dendritic cells confers antigen-presenting ability on basophils |pdf=|usr=}}{{28096423}} gab.com Text Trogocytosis of peptide MHC class II complexes from dendritic cells confers antigen-presenting ability on basophils JO: Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=28096423 #FOAvip Recent studies have revealed that basophils, the rarest granulocytes, have crucial roles in various immune responses. Among their properties, the MHC class II (MHC-II) expression and their function as antigen-presenting cells are matters of considerable controversy. Here we show that basophils indeed express MHC-II on the cell surface, but with little transcription of corresponding genes. This could be achieved by the acquisition of peptide?MHC-II complexes from dendritic cells via cell contact-dependent trogocytosis in vitro and in vivo. The acquired complexes enabled basophils to stimulate and differentiate T cells toward Th2 cells. Thus, the present study clarified the mechanism by which basophils display MHC-II on the cell surface and appears to reconcile some discrepancies observed in previous studies. Twit Text FOAVip Trogocytosis of peptide MHC class II complexes from dendritic cells confers antigen-presenting ability on basophils ????Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=28096423 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28096423 #FOAvip English Wikipedia <ref>{{Cite pmid|28096423}}</ref> Trogocytosis of peptide?MHC class II complexes from dendritic cells confers antigen-presenting ability on basophils #MMPMID28096423 Miyake K; Shiozawa N; Nagao T; Yoshikawa S; Yamanishi Y; Karasuyama H Proc Natl Acad Sci U S A 2017[Jan]; 114 (5): 1111-6 PMID28096423show ga Recent studies have revealed that basophils, the rarest granulocytes, have crucial roles in various immune responses. Among their properties, the MHC class II (MHC-II) expression and their function as antigen-presenting cells are matters of considerable controversy. Here we show that basophils indeed express MHC-II on the cell surface, but with little transcription of corresponding genes. This could be achieved by the acquisition of peptide?MHC-II complexes from dendritic cells via cell contact-dependent trogocytosis in vitro and in vivo. The acquired complexes enabled basophils to stimulate and differentiate T cells toward Th2 cells. Thus, the present study clarified the mechanism by which basophils display MHC-II on the cell surface and appears to reconcile some discrepancies observed in previous studies. äTrogocytosis of peptide?MHC class II complexes from dendritic cells co(epmc).pdf DeepDyve Pubget Overpricing