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10.3346/jkms.2017.32.3.522 http://scihub22266oqcxt.onion/10.3346/jkms.2017.32.3.522 C5290114!5290114 !28145658     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28145658 &cmd=llinks): Failed to open stream: HTTP request failed! 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Frequency and Clinical Characteristics of Hydroxychloroquine Retinopathy in Korean Patients with Rheumatologic Diseases |pdf=|usr=}}{{28145658 }} gab.com Text Frequency and Clinical Characteristics of Hydroxychloroquine Retinopathy in Korean Patients with Rheumatologic Diseases JO: J Korean Med Sci http://www.kidney.de/pget.php?&tw=1&pmid=28145658 #FOAvip This study aimed to evaluate the frequency and clinical characteristics of hydroxychloroquine (HCQ) retinopathy in Korean patients with rheumatologic diseases. We retrospectively reviewed medical records of 310 patients taking HCQ. Ophthalmic examinations included spectral-domain optical coherence tomography (SD-OCT), automated visual field test, and fundus autofluorescence. The severity of retinopathy was categorized as early, moderate, or severe, and the location was categorized as parafoveal, pericentral, or mixed pattern. Among 310 patients, 9 patients (2.9%) were diagnosed as HCQ retinopathy. Among the patients with HCQ use ? 5 years (n = 174), the frequency was 5.2%. Only 1 (11.1%) of the 9 patients was symptomatic. The mean daily dose per kilogram of real body weight of the 9 patients was 5.6 mg, and only 3 had used 6.5 mg or more. Four of the 9 patients had severe HCQ retinopathy. Six of the 9 patients showed pericentral or mixed pattern of retinal damage. Consequently, the frequency of HCQ retinopathy in Korean patients was not low, especially when administered at a high cumulative dose and for a long duration. Screening of HCQ retinopathy by the recommended guidelines that include SD-OCT seems useful and should be done to detect retinal damage earlier in patients with chronic exposure to HCQ. Twit Text FOAVip Frequency and Clinical Characteristics of Hydroxychloroquine Retinopathy in Korean Patients with Rheumatologic Diseases ????J Korean Med Sci http://www.kidney.de/pget.php?&tw=1&pmid=28145658 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28145658 #FOAvip English Wikipedia <ref>{{Cite pmid|28145658 }}</ref> Frequency and Clinical Characteristics of Hydroxychloroquine Retinopathy in Korean Patients with Rheumatologic Diseases #MMPMID28145658 Eo DR ; Lee MG ; Ham DI ; Kang SW ; Lee J ; Cha HS ; Koh E ; Kim SJ J Korean Med Sci 2017[Mar]; 32 (3 ): 522-527 PMID28145658 show ga This study aimed to evaluate the frequency and clinical characteristics of hydroxychloroquine (HCQ) retinopathy in Korean patients with rheumatologic diseases. We retrospectively reviewed medical records of 310 patients taking HCQ. Ophthalmic examinations included spectral-domain optical coherence tomography (SD-OCT), automated visual field test, and fundus autofluorescence. The severity of retinopathy was categorized as early, moderate, or severe, and the location was categorized as parafoveal, pericentral, or mixed pattern. Among 310 patients, 9 patients (2.9%) were diagnosed as HCQ retinopathy. Among the patients with HCQ use ? 5 years (n = 174), the frequency was 5.2%. Only 1 (11.1%) of the 9 patients was symptomatic. The mean daily dose per kilogram of real body weight of the 9 patients was 5.6 mg, and only 3 had used 6.5 mg or more. Four of the 9 patients had severe HCQ retinopathy. Six of the 9 patients showed pericentral or mixed pattern of retinal damage. Consequently, the frequency of HCQ retinopathy in Korean patients was not low, especially when administered at a high cumulative dose and for a long duration. Screening of HCQ retinopathy by the recommended guidelines that include SD-OCT seems useful and should be done to detect retinal damage earlier in patients with chronic exposure to HCQ. |Adult [MESH] |Aged [MESH] |Antirheumatic Agents/*adverse effects/therapeutic use [MESH] |Asian People [MESH] |Drug Dosage Calculations [MESH] |Female [MESH] |Fluorescein Angiography [MESH] |Humans [MESH] |Hydroxychloroquine/*adverse effects/therapeutic use [MESH] |Male [MESH] |Middle Aged [MESH] |Odds Ratio [MESH] |Republic of Korea/epidemiology [MESH] |Retina/diagnostic imaging [MESH] |Retinal Diseases/*chemically induced/diagnostic imaging/epidemiology [MESH] |Retrospective Studies [MESH] |Rheumatic Diseases/drug therapy [MESH] |Severity of Illness Index [MESH] |Tomography, Optical Coherence [MESH]Frequency and Clinical Characteristics of Hydroxychloroquine Retinopat(epmc).pdf DeepDyve Pubget Overpricing