Relevance of epithelial-to-pericyte transition in cancer #MMPMID28197535
Shenoy AK; Lu J
Mol Cell Oncol 2017[]; 4 (1): ä PMID28197535show ga
The relevance of epithelial-to-mesenchymal transition (EMT) in cancer is still under debate. Recently, we reported that EMT bestows key pericyte properties on cancer cells and may thus represent epithelial-to-pericyte transition (EPT). Carcinoma cells undergo EPT to stabilize blood vessels and fuel primary tumor growth. Association of EPT cancer cells with vascular niches may also promote resistance to therapy.