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http://scihub22266oqcxt.onion/ C5274528!5274528!28138201     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Psychopharmacol+Bull 2017 ; 47 (1): 27-32 Nephropedia Template TP {{tp|p=28138201|t=2017. Asenapine for the Control of Physical Aggression: A Prospective Naturalist Pilot Study |pdf=|usr=}}{{28138201}} gab.com Text Asenapine for the Control of Physical Aggression: A Prospective Naturalist Pilot Study JO: Psychopharmacol Bull http://www.kidney.de/pget.php?&tw=1&pmid=28138201 #FOAvip It has been previously purported that higher relative affinity to the dopamine D4 receptor compared to D2 (i.e., D4/D2 affinity ratio > 1) may underlie unique antiaggression potency. Asenapine is a newer antipsychotic that also has D4/D2 affinity ratio > 1. It has demonstrated efficacy in reducing acute agitation in a placebo-controlled study. We performed a prospective naturalistic, pilot, proof of concept study on an inpatient psychiatric unit. Among patients with aggression at time of admission (? 12 on Refined Aggression Questionnaire [RAQ], or ? 2 on Modified Overt Aggression Scale [MOAS]), asenapine treatment was associated with a significant reduction in total aggression as measured by the MOAS (?14.7 ± 11.59 vs. ?5.4 ± 10.12, P = 0.045), and particularly physical aggression (?8.0 ± 5.06 vs. ?0.78 ± 2.40, P < 0.0001) compared to treatment that did not include asenapine. These data suggest that asenapine may be useful in the targeted treatment of aggression, and provide some support for the D4/D2 affinity ratio hypothesis. Twit Text FOAVip Asenapine for the Control of Physical Aggression: A Prospective Naturalist Pilot Study ????Psychopharmacol Bull http://www.kidney.de/pget.php?&tw=1&pmid=28138201 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28138201 #FOAvip English Wikipedia <ref>{{Cite pmid|28138201}}</ref> Asenapine for the Control of Physical Aggression: A Prospective Naturalist Pilot Study #MMPMID28138201 Amon JS; Johnson SB; El-Mallakh RS Psychopharmacol Bull 2017[Jan]; 47 (1): 27-32 PMID28138201show ga It has been previously purported that higher relative affinity to the dopamine D4 receptor compared to D2 (i.e., D4/D2 affinity ratio > 1) may underlie unique antiaggression potency. Asenapine is a newer antipsychotic that also has D4/D2 affinity ratio > 1. It has demonstrated efficacy in reducing acute agitation in a placebo-controlled study. We performed a prospective naturalistic, pilot, proof of concept study on an inpatient psychiatric unit. Among patients with aggression at time of admission (? 12 on Refined Aggression Questionnaire [RAQ], or ? 2 on Modified Overt Aggression Scale [MOAS]), asenapine treatment was associated with a significant reduction in total aggression as measured by the MOAS (?14.7 ± 11.59 vs. ?5.4 ± 10.12, P = 0.045), and particularly physical aggression (?8.0 ± 5.06 vs. ?0.78 ± 2.40, P < 0.0001) compared to treatment that did not include asenapine. These data suggest that asenapine may be useful in the targeted treatment of aggression, and provide some support for the D4/D2 affinity ratio hypothesis. äAsenapine for the Control of Physical Aggression: A Prospective Natura(epmc).pdf DeepDyve Pubget Overpricing