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10.1016/j.immuni.2016.04.012 http://scihub22266oqcxt.onion/10.1016/j.immuni.2016.04.012 C5260013!5260013!27192567     free     free     free       Immunity 2016 ; 44 (5): 1020-33 Nephropedia Template TP {{tp|p=27192567|t=2016. T Cell Cosignaling Molecules in Transplantation |pdf=|usr=}}{{27192567}} gab.com Text T Cell Cosignaling Molecules in Transplantation JO: Immunity http://www.kidney.de/pget.php?&tw=1&pmid=27192567 #FOAvip The ultimate outcome of alloreactivity vs. tolerance following transplantation is potently influenced by the constellation of cosignaling molecules expressed by immune cells during priming with alloantigen, and the net sum of costimulatory and coinhibitory signals transmitted via ligation of these molecules. Intense investigation over the last two decades has yielded a detailed understanding of the kinetics, cellular distribution, and intracellular signaling networks of cosignaling molecules such as the CD28, TNF and TIM families of receptors in alloimmunity. More recent work has better defined the cellular and molecular mechanisms by which engagement of cosignaling networks serve to either dampen or augment alloimmunity. These findings will likely aid in the rational development of novel immunomodulatory strategies to prolong graft survival and improve outcomes following transplantation. Twit Text FOAVip T Cell Cosignaling Molecules in Transplantation ????Immunity http://www.kidney.de/pget.php?&tw=1&pmid=27192567 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27192567 #FOAvip English Wikipedia <ref>{{Cite pmid|27192567}}</ref> T Cell Cosignaling Molecules in Transplantation #MMPMID27192567 Ford ML Immunity 2016[May]; 44 (5): 1020-33 PMID27192567show ga The ultimate outcome of alloreactivity vs. tolerance following transplantation is potently influenced by the constellation of cosignaling molecules expressed by immune cells during priming with alloantigen, and the net sum of costimulatory and coinhibitory signals transmitted via ligation of these molecules. Intense investigation over the last two decades has yielded a detailed understanding of the kinetics, cellular distribution, and intracellular signaling networks of cosignaling molecules such as the CD28, TNF and TIM families of receptors in alloimmunity. More recent work has better defined the cellular and molecular mechanisms by which engagement of cosignaling networks serve to either dampen or augment alloimmunity. These findings will likely aid in the rational development of novel immunomodulatory strategies to prolong graft survival and improve outcomes following transplantation. äT Cell Cosignaling Molecules in Transplantation (epmc).pdf DeepDyve Pubget Overpricing