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10.1073/pnas.1612195114 http://scihub22266oqcxt.onion/10.1073/pnas.1612195114 C5255621!5255621!28031488     free     free     free       Proc+Natl+Acad+Sci+U+S+A 2017 ; 114 (3): 562-7 Nephropedia Template TP {{tp|p=28031488|t=2017. CD74 is a novel transcription regulator |pdf=|usr=}}{{28031488}} gab.com Text CD74 is a novel transcription regulator JO: Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=28031488 #FOAvip CD74 has been associated with tumor progression and metastasis. Its expression has been suggested to serve as a prognostic factor in many cancers, with higher relative expression behaving as a marker of tumor progression. Our previous studies showed that stimulation of CD74 expressed on chronic lymphocytic cells initiates a signaling cascade leading to chronic lymphocytic survival. The present study demonstrates that CD74?s cytoplasmic domain binds chromatin and regulates transcription and expression of genes involved in immune regulation, cell survival, and hematopoietic cancers. Further analysis of these processes will identify new targets that regulate tumor cell maintenance. Twit Text FOAVip CD74 is a novel transcription regulator ????Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=28031488 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28031488 #FOAvip English Wikipedia <ref>{{Cite pmid|28031488}}</ref> CD74 is a novel transcription regulator #MMPMID28031488 Gil-Yarom N; Radomir L; Sever L; Kramer MP; Lewinsky H; Bornstein C; Blecher-Gonen R; Barnett-Itzhaki Z; Mirkin V; Friedlander G; Shvidel L; Herishanu Y; Lolis EJ; Becker-Herman S; Amit I; Shachar I Proc Natl Acad Sci U S A 2017[Jan]; 114 (3): 562-7 PMID28031488show ga CD74 has been associated with tumor progression and metastasis. Its expression has been suggested to serve as a prognostic factor in many cancers, with higher relative expression behaving as a marker of tumor progression. Our previous studies showed that stimulation of CD74 expressed on chronic lymphocytic cells initiates a signaling cascade leading to chronic lymphocytic survival. The present study demonstrates that CD74?s cytoplasmic domain binds chromatin and regulates transcription and expression of genes involved in immune regulation, cell survival, and hematopoietic cancers. Further analysis of these processes will identify new targets that regulate tumor cell maintenance. äCD74 is a novel transcription regulator (epmc).pdf DeepDyve Pubget Overpricing