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10.1091/mbc.E16-07-0547

http://scihub22266oqcxt.onion/10.1091/mbc.E16-07-0547
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C5231902!5231902!27903773
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suck abstract from ncbi


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pmid27903773      Mol+Biol+Cell 2017 ; 28 (2): 346-55
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  • NLK-mediated phosphorylation of HDAC1 negatively regulates Wnt signaling #MMPMID27903773
  • Masoumi KC; Daams R; Sime W; Siino V; Ke H; Levander F; Massoumi R
  • Mol Biol Cell 2017[Jan]; 28 (2): 346-55 PMID27903773show ga
  • Primary embryonic fibroblast cells isolated from NLK-deficient mice proliferate faster and have a shorter cell cycle than wild-type cells. Nemo-like kinase and HDAC1 together negatively regulate Wnt signaling via Tcf/Lef transcription repression and prevent aberrant proliferation of fibroblast cells.
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