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Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 J+Cell+Biol 2017 ; 216 (1): 199-215 Nephropedia Template TP
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A reverse signaling pathway downstream of Sema4A controls cell migration via Scrib #MMPMID28007914
Sun T; Yang L; Kaur H; Pestel J; Looso M; Nolte H; Krasel C; Heil D; Krishnan RK; Santoni MJ; Borg JP; Bünemann M; Offermanns S; Swiercz JM; Worzfeld T
J Cell Biol 2017[Jan]; 216 (1): 199-215 PMID28007914show ga
Semaphorins are ligands for their receptors, plexins. In this study, Sun et al. show that a transmembrane semaphorin, Sema4A, transduces signals in a reverse manner to control migration of cancer and dendritic cells via the cell polarity protein Scrib.