Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27643740
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27643740
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Hemoglobin
2016 ; 40
(5
): 295-299
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Renal Failure in Sickle Cell Disease: Prevalence, Predictors of Disease,
Mortality and Effect on Length of Hospital Stay
#MMPMID27643740
Yeruva SL
; Paul Y
; Oneal P
; Nouraie M
Hemoglobin
2016[Sep]; 40
(5
): 295-299
PMID27643740
show ga
Renal dysfunction in sickle cell disease is not only a chronic comorbidity but
also a mortality risk factor. Though renal dysfunction starts early in life in
sickle cell patients, the predictors that can identify sickle cell disease
patients at risk of developing renal dysfunction is not known. We used the Truven
Health MarketScan(®) Medicaid Databases from 2007 to 2012. Incidence of new acute
renal failure (ARF) and chronic kidney disease (CKD) was calculated in this
cohort. There were 9481 patients with a diagnosis of sickle cell disease
accounting for 64,201 hospital admissions, during the study period. Both ARF and
CKD were associated with higher risk of inpatient mortality, longer duration of
the hospital stay and expensive hospitalizations. The yearly incidence of new ARF
in sickle cell disease patients was 1.4% and annual CKD incidence was 1.3%. The
annual rate of new ARF and CKD in the control group was 0.4 and 0.6%,
respectively. The most important predictors of new CKD were proteinuria, ARF and
hypertension. Chronic kidney disease, hypertension and sickle cell crisis were
the most important predictors of new ARF. The annual rate of incidences of ARF
and CKD were 2- to 3-fold higher in sickle cell disease compared to the non
sickle cell disease group. Besides the common risk factors for renal disease in
the general population, it is imperative to monitor the sickle cell disease
patients with more severe disease to prevent them from developing renal
dysfunction.
|Acute Kidney Injury/epidemiology/prevention & control
[MESH]
|Anemia, Sickle Cell/*complications
[MESH]
|Cohort Studies
[MESH]
|Hospitalization
[MESH]
|Humans
[MESH]
|Hypertension/complications
[MESH]
|Incidence
[MESH]
|Length of Stay
[MESH]
|Mortality
[MESH]
|Prevalence
[MESH]
|Proteinuria/complications
[MESH]
|Renal Insufficiency, Chronic/epidemiology/prevention & control
[MESH]