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10.1093/bioinformatics/btw398 http://scihub22266oqcxt.onion/10.1093/bioinformatics/btw398 C5181555!5181555!27423895     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Bioinformatics 2016 ; 32 (22): 3495-7 Nephropedia Template TP {{tp|p=27423895|t=2016. TopPIC: a software tool for top-down mass spectrometry-based proteoform identification and characterization |pdf=|usr=}}{{27423895}} gab.com Text TopPIC: a software tool for top-down mass spectrometry-based proteoform identification and characterization JO: Bioinformatics http://www.kidney.de/pget.php?&tw=1&pmid=27423895 #FOAvip Summary: Top-down mass spectrometry enables the observation of whole complex proteoforms in biological samples and provides crucial information complementary to bottom-up mass spectrometry. Because of the complexity of top-down mass spectra and proteoforms, it is a challenging problem to efficiently interpret top-down tandem mass spectra in high-throughput proteome-level proteomics studies. We present TopPIC, a tool that efficiently identifies and characterizes complex proteoforms with unknown primary structure alterations, such as amino acid mutations and post-translational modifications, by searching top-down tandem mass spectra against a protein database.Availability and Implementation:http://proteomics.informatics.iupui.edu/software/toppic/Contact:xw liu@iupui.eduSupplementary information:Supplementary data are available at Bioinformatics online. Twit Text FOAVip TopPIC: a software tool for top-down mass spectrometry-based proteoform identification and characterization ????Bioinformatics http://www.kidney.de/pget.php?&tw=1&pmid=27423895 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27423895 #FOAvip English Wikipedia <ref>{{Cite pmid|27423895}}</ref> TopPIC: a software tool for top-down mass spectrometry-based proteoform identification and characterization #MMPMID27423895 Kou Q; Xun L; Liu X Bioinformatics 2016[Nov]; 32 (22): 3495-7 PMID27423895show ga Summary: Top-down mass spectrometry enables the observation of whole complex proteoforms in biological samples and provides crucial information complementary to bottom-up mass spectrometry. Because of the complexity of top-down mass spectra and proteoforms, it is a challenging problem to efficiently interpret top-down tandem mass spectra in high-throughput proteome-level proteomics studies. We present TopPIC, a tool that efficiently identifies and characterizes complex proteoforms with unknown primary structure alterations, such as amino acid mutations and post-translational modifications, by searching top-down tandem mass spectra against a protein database.Availability and Implementation:http://proteomics.informatics.iupui.edu/software/toppic/Contact:xw liu@iupui.eduSupplementary information:Supplementary data are available at Bioinformatics online. äTopPIC: a software tool for top-down mass spectrometry-based proteofor(epmc).pdf DeepDyve Pubget Overpricing