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10.1093/bioinformatics/btw398 http://scihub22266oqcxt.onion/10.1093/bioinformatics/btw398 C5181555!5181555 !27423895     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27423895 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Bioinformatics 2016 ; 32 (22 ): 3495-3497 Nephropedia Template TP {{tp|p=27423895 |t=2016. TopPIC: a software tool for top-down mass spectrometry-based proteoform identification and characterization |pdf=|usr=}}{{27423895 }} gab.com Text TopPIC: a software tool for top-down mass spectrometry-based proteoform identification and characterization JO: Bioinformatics http://www.kidney.de/pget.php?&tw=1&pmid=27423895 #FOAvip Top-down mass spectrometry enables the observation of whole complex proteoforms in biological samples and provides crucial information complementary to bottom-up mass spectrometry. Because of the complexity of top-down mass spectra and proteoforms, it is a challenging problem to efficiently interpret top-down tandem mass spectra in high-throughput proteome-level proteomics studies. We present TopPIC, a tool that efficiently identifies and characterizes complex proteoforms with unknown primary structure alterations, such as amino acid mutations and post-translational modifications, by searching top-down tandem mass spectra against a protein database. AVAILABILITY AND IMPLEMENTATION: http://proteomics.informatics.iupui.edu/software/toppic/ CONTACT: xwliu@iupui.eduSupplementary information: Supplementary data are available at Bioinformatics online. Twit Text FOAVip TopPIC: a software tool for top-down mass spectrometry-based proteoform identification and characterization ????Bioinformatics http://www.kidney.de/pget.php?&tw=1&pmid=27423895 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27423895 #FOAvip English Wikipedia <ref>{{Cite pmid|27423895 }}</ref> TopPIC: a software tool for top-down mass spectrometry-based proteoform identification and characterization #MMPMID27423895 Kou Q ; Xun L ; Liu X Bioinformatics 2016[Nov]; 32 (22 ): 3495-3497 PMID27423895 show ga Top-down mass spectrometry enables the observation of whole complex proteoforms in biological samples and provides crucial information complementary to bottom-up mass spectrometry. Because of the complexity of top-down mass spectra and proteoforms, it is a challenging problem to efficiently interpret top-down tandem mass spectra in high-throughput proteome-level proteomics studies. We present TopPIC, a tool that efficiently identifies and characterizes complex proteoforms with unknown primary structure alterations, such as amino acid mutations and post-translational modifications, by searching top-down tandem mass spectra against a protein database. AVAILABILITY AND IMPLEMENTATION: http://proteomics.informatics.iupui.edu/software/toppic/ CONTACT: xwliu@iupui.eduSupplementary information: Supplementary data are available at Bioinformatics online. |*Proteome [MESH] |*Proteomics [MESH] |Animals [MESH] |Humans [MESH] |Protein Processing, Post-Translational [MESH] |Software [MESH]TopPIC: a software tool for top-down mass spectrometry-based proteofor(epmc).pdf DeepDyve Pubget Overpricing