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10.1083/jcb.201605030

http://scihub22266oqcxt.onion/10.1083/jcb.201605030
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C5166500!5166500!27899413
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suck abstract from ncbi


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pmid27899413      J+Cell+Biol 2016 ; 215 (6): 779-88
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  • Calcium channel regulator Mid1 links TORC2-mediated changes in mitochondrial respiration to autophagy #MMPMID27899413
  • Vlahakis A; Lopez Muniozguren N; Powers T
  • J Cell Biol 2016[Dec]; 215 (6): 779-88 PMID27899413show ga
  • Rapamycin-insensitive TORC2 signaling promotes amino acid starvation?induced autophagy through inhibition of the calcium-dependent phosphatase calcineurin. Vlahakis et al. show that this regulation requires the ER calcium channel regulatory protein Mid1, which couples mitochondrial ROS accumulation in TORC2 mutants to calcineurin activation and autophagy repression.
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