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10.1080/23723556.2016.1227894

http://scihub22266oqcxt.onion/10.1080/23723556.2016.1227894
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C5160400!5160400!28090577
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suck abstract from ncbi


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pmid28090577      Mol+Cell+Oncol 2016 ; 3 (6): ä
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  • Modeling intratumor heterogeneity through CRISPR-barcodes #MMPMID28090577
  • Guernet A; Aaronson SA; Anouar Y; Grumolato L
  • Mol Cell Oncol 2016[]; 3 (6): ä PMID28090577show ga
  • We have devised a barcoding strategy to recapitulate cancer evolution through the emergence of subclonal mutations of interest, whose effects can be monitored in a dynamic manner. This approach can be easily adapted for a variety of applications, including combined modeling of multiple mechanisms of drug resistance or repair of oncogenic driver mutations in addicted cancer cells.
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